Protein Alignment CG30020 and znf827

DIOPT Version :10

• Sequence 1: NP_610627.2
• Gene: CG30020 / 36156
• FlyBaseID: FBgn0050020
• Length: 1309
• Species: Drosophila melanogaster
• Sequence 2: XP_005160034.2
• Gene: znf827 / 565077
• ZFINID: ZDB-GENE-080728-3
• Length: 1424
• Species: Danio rerio
• Alignment Length: 1219
• Identity: 255/1219 - (20%)
• Similarity: 403/1219 - (33%)
• Gaps: 404/1219 - (33%)

  Fly   266 SVDSLTSTLPPMDTPNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNSSSNVN-VSLQ---- 325
            |..|.:|||..: :..||         :.|.|||..|        :.:|::.|.:: ||:.
Zfish   307 SPQSASSTLAAL-SKKVS---------ERSQQQVGSS--------EHQPSAGSFLSLVSMTSSAA 353

  Fly   326 -----------NLLSSHNDPMDI-----DVNELI------------VEEMMPQI---RIKP---- 355
                       |||:...:|..:     ||..|:            ::.::|.:   |.||
Zfish   354 LLKEVAARAAGNLLADKKEPALVLGASEDVKPLLDRNQKVPTPTQAMDLLLPTVPKGRAKPSSQA 418

  Fly   356 -------KPAVIGTSIHKHKCKFCPKTFSTVARLKSHQLTHSNLPKFFCDQCDFYSLRSADLIQH 413
                   ||         .:|..|.......:..|.|.:.|:.|....|..|.|...|..:|..|
Zfish   419 GSPEDGGKP---------FQCPVCGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSH 474

  Fly   414 YKMVHHRVDENGKTGKEQAQGIESRVYSCDMCLFETSTVSQLRTHYK-ERHTVQP-TEVQLRPSW 476
            .|:  |:..:.|:|            :.|::|.|.:|....|:.|.: .:|..:| .:|:..|..
Zfish   475 MKV--HQHQDRGET------------FQCELCPFTSSRHFSLKLHMRCHQHFPRPDLKVKEEPGT 525

  Fly   477 TGE-------------------------PTTTRGVAAKQQTPAKILNHTDIPLGIKYPPGVLETQ 516
            ..|                         ||.::..|....:||:..||..    ||..|...:..
Zfish   526 DTEEGEGLLMGDGGAAGDQAMNTDASTSPTVSQPDARLLASPAEPSNHVQ----IKEEPQERDVS 586

  Fly   517 APLPQPVVHQPMPDPMQQTEPMATTSTTITESGDINVVVDATPLFYAATSNSLLVTNPAPVTTVE 581
            ...|..:..          |..:::|:::..||     :.::|.....|:.||.    :|..|.:
Zfish   587 VMSPFALCR----------ERPSSSSSSLDLSG-----LKSSPPGPGPTAASLF----SPDITTK 632

  Fly   582 ETTG-----TASNHAFGIFPEISEGNLPVNEAVQ-QAPANSSSVSVFGDMQDFIDNTDVAAICTI 640
            ..|.     :|:|.     .|..:|...|.|..| :.|.||.....:...|:....|      |.
Zfish   633 TATDLLIKLSAANQ-----KEALKGPYCVKEEPQAEEPLNSQRGPSYSFCQEGPPGT------TK 686

  Fly   641 P-ADGMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDDTVADEEDEADNEDENDNNDAATDQN 704
            | .:|.|::....::..:.|:.:   |..|.....|                    ||..|..||
Zfish   687 PREEGSPMLGKSSLLSQDINVKV---ASELLMKLSE--------------------NNKDACVQN 728

  Fly   705 LLLTSDDDDVDDFDD--EQSKHL-----QKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCT 762
            :::.::..:||...|  ..|.||     ..|    |.||                      |...
Zfish   729 VIVKAEPMEVDPPLDLASPSSHLLGFSTSGP----CEKK----------------------EPMV 767

  Fly   763 NLYNMKRLLIKHYKTVHKRMPTRDM----VQAK---------GDKVSVARTNIEKLYPGRIKNPM 814
            ||.:            |...|..|:    :..|         .:|||.|..|.:....| |.:|.
Zfish   768 NLPD------------HLPRPQNDLFSQDISVKMASELLFKLSEKVSKANENKDNASFG-IHSPS 819

  Fly   815 L--MCAKCPFECESDSEMRKHLNAHHGI------------NDGVSE-HANEVFIIRKLPFECPRC 864
            |  ...:.||...|.|.......:...:            .:|:|: ..||..      |.||.|
Zfish   820 LDDRFRQSPFSTRSKSSSPAEAGSSSRVPQQDPEKVSSEPGNGLSQWRLNEQL------FPCPVC 878

  Fly   865 IRSFAAKTTLSRHLQ--------RSHLVD-------TIIEMQTPHCGEAITTTMATSSSTISEPV 914
            .:.|..:.||||||.        :.||..       .:.:..|.|..:.:.|       .:.:.|
Zfish   879 GKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTIHSVKLVNT-------DVEQIV 936

  Fly   915 NSVTVDGQ-----------HNEMMQTDVGAEKMTEALGNGDGNEEGGTDDGTGVKAEPAVPEEEL 968
            .:||.||.           |....||:..|:.::....:.|                     :|.
Zfish   937 TAVTNDGPELKNCPYYYSCHVCGFQTEFNAQFVSHMSLHVD---------------------KEQ 980

  Fly   969 DPVTLDAAT----AVTTTAIAAAISAAAAATATSLESPVATTASSSTTLFPTPTPFDFDYDIMRD 1029
            ...:|..:|    .|....:.|.|||..|  ..:..||::.|.|:|::|
Zfish   981 WMFSLCCSTCEYVGVDEAEMKAHISAGHA--GLNSRSPLSETKSTSSSL---------------- 1027

  Fly  1030 EAQQSSPNIHDVSKALSDNASSS-----CPINESYKLLSTTALETSPAKGLRSNSRLHRSSIH-- 1087
                         .||||:.:||     ...||..|.|      .:|...:.|.|.|...:..
Zfish  1028 -------------SALSDSLNSSEGGDVAQGNEELKSL------LAPPSSVGSQSSLGPGAEEKA 1073

  Fly  1088 ----ICKLCNQTFDELGKLVKHEMELHSNTERSRWGYQHKCAICNTSYRTLTLLKFHMKRHSNRK 1148
                .|..||..........:| :::|..|.      ..:|.:|:...:|...|..|.|.|:...
Zfish  1074 EKGFECVFCNFVCKTRPMYERH-LQIHLITR------MFECDVCHKFMKTPEQLLEHKKCHTVPA 1131

  Fly  1149 S--QCKLCPKSFVTIAELERHTKAKHSKDKTLRCFMDGCRKTFAFKHHLIRHQKASHLSTRYICP 1211
            .  :|.||..|....|.:|.|.|..:..:  .||.:  |:..:|.:..|.||.:|..|...|.|.
Zfish  1132 GGLKCPLCIYSTNRPAAMEGHLKTHYKME--YRCRI--CQAVWANQAELERHTRAHRLGNHYKCE 1192

  Fly  1212 VCNKEEKSNVHLKNHMSVHKGEITYKCPKCDRSYLRRGRLVTHALIIHDLR---------FTT-- 1265
            .|....|:...|..|:.||.||..:.|.:|..|..|:..|..|..:.|..|         |||
Zfish  1193 QCGYLSKTANKLIEHVRVHTGERPFHCDRCSYSCKRKDNLNLHKRLKHAPRQTFGCAQCPFTTTH 1257

  Fly  1266 ---------EELGNLSSLATNQARPNDLKVATP-VGLLDGRKDVSGASE 1304
                     :..|...|....:|||     .|| .|||:.....||:.:
Zfish  1258 PFVYSRHVKKHQGGEGSAEEGEARP-----GTPHPGLLERGGSSSGSGD 1301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..103	CDD:214871
		C2H2 Zn finger	369..389	CDD:275368	4/19 (21%)
		C2H2 Zn finger	397..418	CDD:275368	7/20 (35%)
		C2H2 Zn finger	442..460	CDD:275368	6/17 (35%)
		C2H2 Zn finger	730..750	CDD:275368	3/19 (16%)
		C2H2 Zn finger	758..777	CDD:275368	3/18 (17%)
		C2H2 Zn finger	1089..1110	CDD:275368	4/20 (20%)
		C2H2 Zn finger	1124..1144	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1151..1172	CDD:275368	8/20 (40%)
		C2H2 Zn finger	1180..1203	CDD:275368	7/22 (32%)
		C2H2 Zn finger	1210..1230	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1238..1254	CDD:275368	5/15 (33%)
znf827	XP_005160034.2	None