|
Fly 21 YKLSCRCCLKTNVEYVKLDSVSVARSLDPADATEKIPLLRCLLFCVSADNAPELPQHICLECSKS 85
|....|..:||: |:.||.:.|:...:.::: ||:.....|..|.
Human 460 YMKHLRTQMKTH------DAESVLKHLEACSSVQRV--------CVTTSETQEAEQG-------- 502
Fly 86 LQVAYYFLQNALRAHEILCRKLCPKVSKRLNGTLAQEQEKPACAEPVQPLKTMRHECQVCGVVLY 150
|.:.|..:.....|..|.: :|: :..|| |..||.|..
Human 503 --------QGSARPPDSGLHSLTVKPA---SGS------QTLCA------------CTDCGQVAT 538
Fly 151 NRLELKQHIRQ-HAEGLSYNCKLCSFTSLKQRTLFEH-YVTMHNMPLS---------------QA 198
||.:|:.|::: ||..:.:.|:.|.|:|:.:|.|.|| :...|....| ..
Human 539 NRTDLEIHVKRCHAREMKFYCRTCDFSSMSRRDLDEHLHSNQHQQTASVLSCQCCSFISLDEINL 603
Fly 199 EEYVKSKHLPAPKEEEVKAVCT------LEDMELLIPTVLRPEDYVQPHPHIDNDQLRDIDHQLA 257
.:::|.|| .:..:|| |.:.:: |::.....||:
Human 604 RDHMKEKH-------NMHFLCTPCNLFFLSEKDV--------EEHKATEKHIN------------ 641
Fly 258 VSMDEPVPSVDSLTSTLPPMDTPNVSIGTEYLVLPDGSLQQVNGSGVVIEYIDDSKPNSSSNVNV 322
|:.:| .::.|..|.| .:.| ||..:|:..|.. |.:|||...|...
Human 642 -SLVQP-KTLQSSNSDL-VLQT-----------LPLSTLESENAK----ESMDDSGKASQEE--- 685
Fly 323 SLQNLLSSHNDPMDIDVNELIVEEMMPQIRIKPKPAVIGTSIHKHKCKFC-PKTFSTVARLKSHQ 386
.|::.:|..| ::|...|| :.:||.| .||.|:....:..:
Human 686 PLKSRVSHGN-----------------EVRHSSKP--------QFQCKKCFYKTRSSTVLTRHIK 725
Fly 387 LTHSNLPKFFCDQCDFYSLRSADLIQHYKMVHHRVDENGK---TGKEQAQGIESRVYSCDMCL-- 446
|.|.....|.|..|:.|||....:.:|.|...|. ||.| .|....:.||. :|:
Human 726 LRHGQDYHFLCKACNLYSLSKEGMEKHIKRSKHL--ENAKKNNIGLSFEECIER------VCIGA 782
Fly 447 ------FETSTVSQLRTH---------YKERHTVQPTEVQLRPSWTGEPTTTRGVAAKQQTPAKI 496
|:.|...::..| |.|:..:...|:......|.:.........|:..|...
Human 783 NDKKEEFDVSGNGRIEGHIGVQLQEHSYLEKGMLASEELSQSGGSTKDDELASTTTPKRGRPKGN 847
Fly 497 LNHTDIPLGIKYPPGVLETQAPLPQPVVHQPMPDPMQQTEPMATTSTTIT------ESGDINVVV 555
::.|....|: :|::.|.:| .|...:.:.
Human 848 ISRTCSHCGL-------------------------------LASSITNLTVHIRRKHSHQYSYLC 881
Fly 556 DATPLFYAATSNSL---LVTNPAPVTTVEETTGTASNHAFGIFPEISEGNLPVNEAVQQAPANSS 617
.... :|..|...: ..|.........|.:|..|: :|..| |...:::....|:.
Human 882 KVCK-YYTVTKGDMERHCATKKHKGRVEIEASGKHSS-------DIIVG--PEGGSLEAGKKNAG 936
Fly 618 SVSVFGDMQDFIDNTDVAAICTIPADG-MPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDDTV 681
|.....|.. ...||:. ..|::..| ...|::.:.||:|...:.|.:..:
Human 937 SAVTMSDEH-----------ANKPAESPTSVLEKPD-----RGNSIEAEVENVFHSLDGEVNSHL 985
Fly 682 ADEEDEADNEDEN--DNNDAATDQNLLLTSDDDDVD-DFDDEQSKHLQKPYCIYCNKKFTSQYKF 743
.|::::..:|.|: ...|..:.:::..|.::..:. :|....|..|: ::..:|.|.:::|
Human 986 LDKKEQISSEPEDFAQPGDVYSQRDVTGTGENKCLHCEFSAHSSASLE----LHVKRKHTKEFEF 1046
Fly 744 ENHMFVHRGLAPYRCELCTNLYNMKRLLIKHYKTVHKRMPTRDMVQAKGDKVSVA---------- 798
.|..|......:|.:.:|..|...:|..:..:.:...:...|
Human 1047 -------------YCMACDYYAVTRREMTRHAATEKHKMKRQSYLNSANVEAGSADMSKNIIMPE 1098
Fly 799 ---RTNIE--KLYPGRIKNPMLM--CAKCPFECESDS-EMRKHLNAHHGINDGVSEHANEVFIIR 855
:.|.| ::..|:..:.:.. .|.|....|:.: :|.|.|.|...:.....|.:|
Human 1099 EEHQQNSEEFQIISGQPSDTLKSRNAADCSILNENTNLDMSKVLCAADSVEVETEEESN------ 1157
Fly 856 KLPFECPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPHCGEAITTTMAT---------SSSTIS 911
|....:.....|::.:.|.:.:.: |.::.||:: :.::.|
Human 1158 ------------FNEDHSFCETFQQAPVKDKVRKPE-----EMMSLTMSSNYGSPSRFQNENSGS 1205
Fly 912 EPVNSVTVDGQHNEMMQTDVGAEKMTEALGNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDA- 975
..:|..|....|. :..|.| |......|.| |...||.|| ||...|.|||||.
Human 1206 SALNCETAKKNHE--ISNDAG-ELRVHCEGEG-----GNAGDGGGV-----VPHRHLCPVTLDGE 1257
Fly 976 ATAVTTTAIAAAISAA----------AAATATSLE------------------------------ 1000
.:|.:...:...|:.. ..|....||
Human 1258 RSAESPVLVVTRITREQGNLESGGQNRVARGHGLEDLKGVQEDPVLGNKEILMNSQHETEFILEE 1322
Fly 1001 -SPVATTASSSTTLFPTPTPFD-----------FDYDIMR----------DEAQQ---------S 1034
.|.:.:...|:.::.|....| ||..|:| |:::: |
Human 1323 DGPASDSTVESSDVYETIISIDDKGQAMYSFGRFDSSIIRIKNPEDGELIDQSEEGLIATGVRIS 1387
Fly 1035 SPNIHDVSKALSDNASSSCPINESYKL--------------LSTTALETSP-----------AKG 1074
...:.|.::.:....|....|.||.:: |:.......| .|.
Human 1388 ELPLKDCAQGVKKKKSEGSSIGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKS 1452
Fly 1075 LRSNSRLHR---SSIHI------------------CKLCNQTFD------------------ELG 1100
..:.|.||: |:.|: |..|.:.|| |:.
Human 1453 FYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEELLREVN 1517
Fly 1101 KLVKHEMELHSNTERSRWGYQHKCAICNTSYRTLTLLKF--HMKRHSNRKS-QCKLCPKSFVTIA 1162
|.:..:.| ..|.||.. ...:.|..|....|:...:.| |::.|:..|. :||:|..:...:.
Human 1518 KYIVEDTE-QINREREE-NQGNVCKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLG 1580
Fly 1163 ELERHTKAKHSKDKTLRCFMDGCRKTFAFKHHLIRHQKASH-----LSTRYICPVCNKEEKSNVH 1222
:...|.| :|...:..:|.: |...|..|.||..|....| ...::.|.:|::.......
Human 1581 DARNHVK-RHLGMREYKCHV--CGVAFVMKKHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWA 1642
Fly 1223 LKNHMSVHKGEITYKC--PKCDRSYLRRGRLVTH 1254
|.|||.:|.||..:|| |.|..|:|....:..|
Human 1643 LNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDH 1676
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