DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30020 and si:dkeyp-84f3.5

DIOPT Version :9

Sequence 1:	NP_610627.2	Gene:	CG30020 / 36156	FlyBaseID:	FBgn0050020	Length:	1309	Species:	Drosophila melanogaster
Sequence 2:	NP_001313282.1	Gene:	si:dkeyp-84f3.5 / 334144	ZFINID:	ZDB-GENE-050208-162	Length:	580	Species:	Danio rerio

Alignment Length:	459	Identity:	92/459 - (20%)
Similarity:	161/459 - (35%)	Gaps:	101/459 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   937 TEALGNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTT-------TAIAAAISAA--A 992
            |:.|..||...  .|:.|.|.:..|.:.|.    :.:...|.|.:       :::..:|..|  .
Zfish     8 TQELRGGDAFI--CTECGEGFRLYPKLVEH----MAIHGLTGVFSSDGISNGSSVNPSIEVALHE 66

  Fly   993 AATATSLESPVATTASSSTTLFPTPTPFDF-----DYDIMRDEAQQSSPNIHDVSK-ALSDNASS 1051
            ..|.|.::..|   .|:.|.||..|.|..|     ...|:..:..:..|.::...: ......|.
Zfish    67 NGTLTVVDRSV---LSNFTFLFGKPQPKRFCPPPSQETIVPSKMPEKEPALYKCDRCGQLFKTSK 128

  Fly  1052 SCPINESYKLLSTTALETSPAKGLRSNSRLH-------RSSIHICKLCNQTFDELGKLVKHEMEL 1109
            |..:::.|:.|......|...|.|.....|.       ....:.|..|.:.|.....|:.|:.:.
Zfish   129 SLHLHQQYRALEQGFKCTLCCKVLNDRESLQNHLQNHAHERFYSCGHCGKRFLRQDSLLSHQKQW 193

  Fly  1110 HSNT-----------ERSRWGYQHKCAICNTSYRTLTLLKFHMKRHS------------------ 1145
            |.:.           :.:.....:.|..|...:..|:.|:.|:..||
Zfish   194 HGSASSRILSRSQEDQENSMDRSYPCKSCGLRFFWLSDLQSHLNSHSRVNKSPNEVMQDQALGEE 258

  Fly  1146 NRK-------SQ-----CKLCPKSFVTIAELERHTKAKHS-----KD------KTLRCFMDGCRK 1187
            |||       ||     |.||.::|:..::|..|.|.:|.     ||      |..:.:....|.
Zfish   259 NRKIDDNSVISQFNEPCCGLCGQNFLNTSDLREHHKVEHPDEIEVKDSSVLPAKAKQQYHGVMRH 323

  Fly  1188 TFAFKHHLI----------RHQKASHLSTRYICPVCNKEEKSNVHLKNHMSVHKGEITYKCPKCD 1242
            ..|.:|..:          |..:|::....:.|..|::....:..|..||..|||.: :.|..|.
Zfish   324 MVAKQHKQLLRVNIKGKPKRINRATYTGKLFSCKHCHRVFVHSSSLSRHMRYHKGTL-HACVYCG 387

  Fly  1243 RSYLRRGRLVTHALIIH--DLRFTTEELGNLSSLATNQARPNDLKVATPVGLLDGRKDVSGASEE 1305
            |.:.:|..:..|..:.|  :|:..::|...:.. .|.......:|.:|.. ..||.::   ..||
Zfish   388 RHFPQRCDVTRHVAMYHASELQSKSQEESTMEH-ETGNGEQEPMKESTQT-TSDGEQE---DLEE 447

  Fly  1306 NGQP 1309
            ..||
Zfish   448 ENQP 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..106	CDD:285071
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..418	CDD:275368
		C2H2 Zn finger	442..460	CDD:275368
		C2H2 Zn finger	730..750	CDD:275368
		C2H2 Zn finger	758..777	CDD:275368
		C2H2 Zn finger	1089..1110	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1124..1144	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1151..1172	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1180..1203	CDD:275368	5/32 (16%)
		C2H2 Zn finger	1210..1230	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1238..1254	CDD:275368	4/15 (27%)
si:dkeyp-84f3.5	NP_001313282.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100