DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30020 and Zfp513

DIOPT Version :9

Sequence 1:	NP_610627.2	Gene:	CG30020 / 36156	FlyBaseID:	FBgn0050020	Length:	1309	Species:	Drosophila melanogaster
Sequence 2:	NP_001012110.1	Gene:	Zfp513 / 313913	RGDID:	1310456	Length:	541	Species:	Rattus norvegicus

Alignment Length:	694	Identity:	139/694 - (20%)
Similarity:	195/694 - (28%)	Gaps:	272/694 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   603 LPVNEAVQQAPANSSSVSVFGDMQDFIDNTDVAAICTIPADGMPVVDGDDIVIDNNNISLDFDAE 667
            :|..:.....|.....|.|  |.:|..|                  :|...::..:::.|..|.|
  Rat     1 MPRRKQSHPQPVKCEGVKV--DTEDSFD------------------EGPGALVLESDLLLGQDLE 45

  Fly   668 NLFEDFEEEEDDTVADEEDEA----DNEDENDNNDAATDQNLLLTSD----------DDDVDD-- 716
                 |||||::...|..::.    :.:.|.|:..|.......|:.|          :.:|::
  Rat    46 -----FEEEEEEEEGDGHNDQLMGFERDSEGDSQGARPGLPYGLSDDESGGGRALSAESEVEEPA 105

  Fly   717 -FDDEQSKHLQKPYCIYCNK------------------------------KFTSQYK--FENHMF 748
             ...|.......|.|..|..                              .|.|.|.  .:.||.
  Rat   106 RGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPPLPPRLLYSCRLCAFVSHYSSHLKRHMQ 170

  Fly   749 VHRGLAPYRCELC----TNLYNMKRLLIKHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKLYPGR 809
            .|.|..|:||..|    ..|.|:.|         |.|..|       |:|            |.|
  Rat   171 THSGEKPFRCGRCPYASAQLVNLTR---------HTRTHT-------GEK------------PYR 207

  Fly   810 IKNPMLMCAKCPFECESDSEMRKHLNAHHGINDGVSEHANEVFIIRKLPFECPRC-IRSFAAKTT 873
                   |..|||.|.|...:|:|...|.|               ...| .||.| .|..|.:.|
  Rat   208 -------CPHCPFACSSLGNLRRHQRTHTG---------------PPTP-PCPTCGFRCCAPRPT 249

  Fly   874 LSRHLQRSHLVDTIIEMQTPHCGEAITTTMATSSSTISEPVNSVTVDGQHNEMMQTDVGAEKMTE 938
                             :.|...|...|....|...:..|..|:.|.......: .|.|     :
  Rat   250 -----------------RPPSPTEQEGTMPRRSEDALILPDLSLHVPPGGTSFL-PDCG-----Q 291

  Fly   939 ALGNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTTTAIAAAISAAAAATATSLESPV 1003
            ..|.|:|.      .|||  :|| :| |.|.|.|.............:.:..|.....
  Rat   292 LRGEGEGL------CGTG--SEP-LP-ELLFPWTCRGCGQELEEGEGSRLGTAMCGRC------- 339

  Fly  1004 ATTASSSTTLFPTPTPFDFDYDIMRDEAQQSSPNIHDVSKALSDNASSSCPINESYKLLSTTALE 1068
                                   ||.|               |....|..|...|.|..:
  Rat   340 -----------------------MRGE---------------SGGGGSGGPQGPSDKGFA----- 361

  Fly  1069 TSPAKGLRSNSRLHRSSIHICKLCNQTFDELGKLVKHEMELHSNTERSRWGYQHKCAICNTSYRT 1133
                                |.||.........|.:| |:.||..:..|      ||.|..:...
  Rat   362 --------------------CSLCPFATHYPNHLARH-MKTHSGEKPFR------CARCPYASAH 399

  Fly  1134 LTLLKFHMKRHSNRKS-QCKLCPKSFVTIAELERHTKAKHSKDKTLRCFMDGCRKTFAFKHHLIR 1197
            |..||.|.:.|:..|. :|.|||.:...:|.|:||.:. ||.||..|
  Rat   400 LDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRI-HSGDKPFR------------------ 445

  Fly  1198 HQKASHLSTRYICPVCNKEEKSNVHLKNHMSVHKGEITYKCPKC 1241
                        |.:||.....:::||.||..|.||..::|..|
  Rat   446 ------------CSLCNYSCNQSMNLKRHMLRHTGEKPFRCATC 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..106	CDD:285071
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..418	CDD:275368
		C2H2 Zn finger	442..460	CDD:275368
		C2H2 Zn finger	730..750	CDD:275368	7/51 (14%)
		C2H2 Zn finger	758..777	CDD:275368	5/22 (23%)
		C2H2 Zn finger	1089..1110	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1124..1144	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1151..1172	CDD:275368	8/20 (40%)
		C2H2 Zn finger	1180..1203	CDD:275368	0/22 (0%)
		C2H2 Zn finger	1210..1230	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1238..1254	CDD:275368	2/4 (50%)
Zfp513	NP_001012110.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..120		25/143 (17%)
		C2H2 Zn finger	152..172	CDD:275368	5/19 (26%)
		zf-H2C2_2	164..189	CDD:290200	8/24 (33%)
		COG5048	176..>228	CDD:227381	22/86 (26%)
		C2H2 Zn finger	180..200	CDD:275368	7/28 (25%)
		zf-H2C2_2	192..217	CDD:290200	14/59 (24%)
		C2H2 Zn finger	208..228	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	6/20 (30%)
		COG5048	<372..>450	CDD:227381	29/115 (25%)
		zf-H2C2_2	374..399	CDD:290200	9/31 (29%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		zf-H2C2_2	402..425	CDD:290200	9/22 (41%)
		COG5048	414..>487	CDD:227381	26/95 (27%)
		C2H2 Zn finger	418..438	CDD:275368	8/20 (40%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		zf-H2C2_2	458..481	CDD:290200	9/20 (45%)
		C2H2 Zn finger	474..493	CDD:275368	2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..541
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100