Protein Alignment CG30020 and ZNF497

DIOPT Version :10

• Sequence 1: NP_610627.2
• Gene: CG30020 / 36156
• FlyBaseID: FBgn0050020
• Length: 1309
• Species: Drosophila melanogaster
• Sequence 2: NP_940860.2
• Gene: ZNF497 / 162968
• HGNCID: 23714
• Length: 498
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 109/531 - (20%)
• Similarity: 167/531 - (31%)
• Gaps: 184/531 - (34%)

  Fly   730 CIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIKHYKTVHKRMPTRDMVQAKGDK 794
            |..|.|.|:.......|..||.|..||.|..|...:.....|.:|.: :|..
Human   108 CGECGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQR-IHSG------------- 158

  Fly   795 VSVARTNIEKLYPGRIKNPMLMCAKCPFECESDSEMRKHLNAHHGINDGVSEHANEVFIIRKLPF 859
                    ||.|         .|.:|.....:.|::..|...|.|:.                ||
Human   159 --------EKPY---------ACRECGKAFRAHSQLIHHQETHSGLK----------------PF 190

  Fly   860 ECPRCIRSFAAKTTLSRHLQRSHLVDTIIEMQTPHCGEAITTTMATSSSTISEPVNSVTVDGQHN 924
            .||.|.:||...|||.:| :|:|..:...|  .|.||:|.:.             ||..:  :|.
Human   191 RCPDCGKSFGRSTTLVQH-RRTHTGEKPYE--CPECGKAFSW-------------NSNFL--EHR 237

  Fly   925 EMMQTDVGAEKMTEALGNGDGNEEGGTDDGTGVKAEPAVPEEELDPVTLDAATAVTTTAIAAAIS 989
            .:                           .||.:....
Human   238 RV---------------------------HTGARPHAC--------------------------- 248

  Fly   990 AAAAATATSLESPVATTASSSTTLFPTPTPFDFDYDIMRD--EAQQSSPNIHDVSKALSDNASSS 1052
                                                  ||  :|...|.|:.:..|..:.....:
Human   249 --------------------------------------RDCGKAFSQSSNLAEHLKIHAGARPHA 275

  Fly  1053 CPINESYKLLSTTALETSPAKGLRSNSRLHRSSIHI-CKLCNQTFDELGKLVKHEMELHSNTERS 1116
            ||  :..|.....|       |||.:.|.|.|.... |..|.:.|.|..:|::|        :|:
Human   276 CP--DCGKAFVRVA-------GLRQHRRTHSSEKPFPCAECGKAFRESSQLLQH--------QRT 323

  Fly  1117 RWGYQ-HKCAICNTSYRTLTLLKFHMKRHSNRKSQ-CKLCPKSFVTIAELERHTKAKHSKDKTLR 1179
            ..|.: .:||.|..::...:.|..|.:.|:..|.. |..|.|:|...:.|..|.:. ||..|...
Human   324 HTGERPFECAECGQAFVMGSYLAEHRRVHTGEKPHACAQCGKAFSQRSNLLSHRRT-HSGAKPFA 387

  Fly  1180 CFMDGCRKTFAFKHHLIRHQKASHLSTR-YICPVCNKEEKSNVHLKNHMSVHKGEITYKCPKCDR 1243
            |  ..|.|.|.....| .|.:.||...| :.|..|.|..:.:..|:.|..:|.||..:.|..|.:
Human   388 C--ADCGKAFRGSSGL-AHHRLSHTGERPFACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSK 449

  Fly  1244 SYLRRGRLVTH 1254
            :::|:..|::|
Human   450 AFVRKSELLSH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30020	NP_610627.2	zf-AD	25..103	CDD:214871
		C2H2 Zn finger	369..389	CDD:275368
		C2H2 Zn finger	397..418	CDD:275368
		C2H2 Zn finger	442..460	CDD:275368
		C2H2 Zn finger	730..750	CDD:275368	5/19 (26%)
		C2H2 Zn finger	758..777	CDD:275368	4/18 (22%)
		C2H2 Zn finger	1089..1110	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1124..1144	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1151..1172	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1180..1203	CDD:275368	6/22 (27%)
		C2H2 Zn finger	1210..1230	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1238..1254	CDD:275368	4/15 (27%)
ZNF497	NP_940860.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..104
		COG5048	107..492	CDD:227381	109/531 (21%)
		C2H2 Zn finger	108..128	CDD:275368	5/19 (26%)
		C2H2 Zn finger	136..156	CDD:275368	4/20 (20%)
		C2H2 Zn finger	164..184	CDD:275368	4/19 (21%)
		C2H2 Zn finger	192..212	CDD:275368	10/20 (50%)
		C2H2 Zn finger	220..240	CDD:275368	7/61 (11%)
		C2H2 Zn finger	248..268	CDD:275368	6/84 (7%)
		C2H2 Zn finger	276..296	CDD:275368	8/28 (29%)
		C2H2 Zn finger	304..324	CDD:275368	7/27 (26%)
		C2H2 Zn finger	332..352	CDD:275368	5/19 (26%)
		C2H2 Zn finger	360..380	CDD:275368	6/20 (30%)
		C2H2 Zn finger	388..408	CDD:275368	6/22 (27%)
		C2H2 Zn finger	416..436	CDD:275368	5/19 (26%)
		C2H2 Zn finger	444..464	CDD:275368	5/17 (29%)
		C2H2 Zn finger	472..492	CDD:275368