DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18004 and INO80E

DIOPT Version :9

Sequence 1:	NP_610625.1	Gene:	CG18004 / 36154	FlyBaseID:	FBgn0033566	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_775889.1	Gene:	INO80E / 283899	HGNCID:	26905	Length:	244	Species:	Homo sapiens

Alignment Length:	255	Identity:	85/255 - (33%)
Similarity:	115/255 - (45%)	Gaps:	81/255 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GLGAGETDFKERYKNLKKKLKFLIYENEYFQDLLHTNQRRLLKVSRDRTFLLDRLLVYEKPAKDS 118
            |...||.|:|::|:|||:||||||||:|.||:.|...||:|||||||::|||||||.||...:||
Human     3 GPADGEVDYKKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKSFLLDRLLQYENVDEDS 67

  Fly   119 SDSDATDSSDSEPASTSGVAGGSQTSKDAIRRKHKDKGAPGIPGVPPHMPTVGAPRGRRRKILTG 183
            ||||||.|||:           |:|           :|.|.:...|       ||:.:|...|.|
Human    68 SDSDATASSDN-----------SET-----------EGTPKLSDTP-------APKRKRSPPLGG 103

  Fly   184 -------MLPANHGIP--AIAAKKQLTATVSPSQQPPQLQTAPKD-VSPGLSQAEIARQLQERRP 238
                   .||.:.|.|  |........::::.|:.||    .|.| ::..|.:....|..:|:||
Human   104 APSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPP----FPSDYLALQLPEPSPLRPKREKRP 164

  Fly   239 ------------------------------------TPL--ELLSPECTSATVPTTMLSD 260
                                                |||  ..:.|....:|||..|.||
Human   165 RLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSD 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18004	NP_610625.1	None
INO80E	NP_775889.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..236		46/195 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149486
Domainoid	1	1.000	106	1.000	Domainoid score	I6640
eggNOG	1	0.900	-	-		E1_2AISN
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008513
OrthoInspector	1	1.000	-	-		oto91712
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21812
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4864
SonicParanoid	1	1.000	-	-		X5692
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.970