DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12344 and gabra5

DIOPT Version :9

Sequence 1:	NP_001286298.1	Gene:	CG12344 / 36145	FlyBaseID:	FBgn0033558	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_005166139.1	Gene:	gabra5 / 799124	ZFINID:	ZDB-GENE-081104-30	Length:	453	Species:	Danio rerio

Alignment Length:	470	Identity:	128/470 - (27%)
Similarity:	209/470 - (44%)	Gaps:	75/470 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SFGLGFILMW------LSEAT-------EAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVI-V 60
            |..:|.:.|.      ||::|       |.:.|.|...|::  |...|...:||  ..|..|. :
Zfish    13 SLWVGVLFMTLTCHLSLSQSTTGTPKESELNDNITVFTRILDGLLDGYDNRLRP--GLGEKVTEI 75

  Fly    61 DFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYF 125
            ..:|||.....::..:|::.:|:|..|.|.:.||     .|:...:.:.|...:..|.|.||.:|
Zfish    76 KTNIFVTSFGPVSDTEMEYTIDVFFRQSWKDERL-----CFKGPMEMLPLNNLLASNIWTPDTFF 135

  Fly   126 LNSKIAEIATLTHKFTS----VTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSS 186
            ||.|    .::.|..|:    :.|..:.|:.|..|:.....|.|:.:.:|||...||:...|::.
Zfish   136 LNGK----KSIAHNMTTPNKLLRLKDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAY 196

  Fly   187 NNQKVKLRWS----DSGVTLNPELKLLQYNL-GQPLELEESDGYMPEKVGNFSRLTVYFRFERQI 246
            ...:|..:|:    .|.|......:|.||:| |.....|:    :....|.::.:..:|..:|:|
Zfish   197 PISEVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTED----ISTSRGQYTVMMAHFYLKRKI 257

  Fly   247 GHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDL 309
            |:.:|||:.|..:.|:||..||||..:::|.|....||.:||:.|:...|  .:|.|||..|:|.
Zfish   258 GYFVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDW 322

  Fly   310 WMAGCMLSVFAALAEFVVVKVL-------DVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGG 367
            ::|.|...||:||.||..|...       |.:...:..:..|..|:.:|.......|.:
Zfish   323 FIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKALEAQQPKKKDPLALSKKPNNFTANI------ 381

  Fly   368 AVRSRKATQTPTTPGQTSLQGNGGPPKPA--RRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFP 430
                .|.....|....|::|......|||  .:::..||:              :|||:||.|||
Zfish   382 ----NKDAAISTISNSTTVQLKSAEAKPAPDPKKTYNSVS--------------KIDKMSRIVFP 428

  Fly   431 ILFFVFVLLYWPILL 445
            :||..|.|:||...|
Zfish   429 VLFGTFNLVYWATYL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	125/464 (27%)
gabra5	XP_005166139.1	Neur_chan_LBD	19..442	CDD:332142	125/461 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910