Protein Alignment alka and Gabrg3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_077346.3
• Gene: Gabrg3 / 79211
• RGDID: 621735
• Length: 467
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 127/463 - (27%)
• Similarity: 206/463 - (44%)
• Gaps: 72/463 - (15%)

  Fly    23 SEATEAHMNYTAKPR-----VVLPPN-----YVKEIRPPSKKG-SPVIVDFSIFVVDINSINVED 76
            ||.:.::..:...|:     |.|..|     |.|::||..  | .|.::|..|:|..|..::..:
  Rat    27 SEDSPSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPDI--GIKPTVIDVDIYVNSIGPVSSIN 89

  Fly    77 MDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFT 141
            |::::|:|..|.|.:|||.     |......:||...:....|.||..|.|||.||...:|....
  Rat    90 MEYQIDIFFAQTWTDSRLR-----FNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQ 149

  Fly   142 SVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTL--NP 204
            .:.::.:..:.|..|:.....||::...:|||...||:...|:....:::..||..:.|..  ..
  Rat   150 LLRIWNDGKILYTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQK 214

  Fly   205 ELKLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 269
            ..:|.|::.   :.|..:...:....|::..:|:||...|::|:..|||:.|..|.|:|||.|||
  Rat   215 SWRLYQFDF---MGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFW 276

  Fly   270 LGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLD 332
            :..||.|.|.||.:|.:||:.|:.|.|  .:|.|:||.|:||::..|.|.|||||.|:..:.
  Rat   277 IKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLN--- 338

  Fly   333 VQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTPTTPGQTSLQGNGGPPKPAR 397
               .|...|.|.:...:.|.:....    ..|    :..|.:.|.|:......::    ||.|..
  Rat   339 ---YYSSCRKPTIRKKKTSLLHPDS----TRW----IPDRISLQAPSNYSLLDMR----PPPPVM 388

  Fly   398 RQSLLSVAWTD-TDTGVEKIM-------------------WR---------EIDKVSRAVFPILF 433
            .....|:.|.: .||.|.:.:                   ||         |:|..||..||..|
  Rat   389 ITLNNSMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSELDSYSRVFFPTSF 453

  Fly   434 FVFVLLYW 441
            .:|.|:||
  Rat   454 LLFNLVYW 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	125/461 (27%)
Gabrg3	NP_077346.3	LIC	50..464	CDD:455710	122/440 (28%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	45/188 (24%)
		Cys-loop	171..185	CDD:349801	5/13 (38%)