Protein Alignment alka and gabra1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_009293960.1
• Gene: gabra1 / 768183
• ZFINID: ZDB-GENE-061013-194
• Length: 470
• Species: Danio rerio
• Alignment Length: 485
• Identity: 132/485 - (27%)
• Similarity: 210/485 - (43%)
• Gaps: 93/485 - (19%)

  Fly    14 GLGFILMWL----------------SEATEAHMNYTAKPRVV--LPPNYVKEIRPP-SKKGSPVI 59
            |.|...:|:                ..|.|...|.|...|::  |...|...:||. .::.:.|.
Zfish    16 GRGAAWLWIWACLLVTNALAGKSSSQNADEQKDNTTVFTRILDSLLDGYDNRLRPGLGERVTEVK 80

  Fly    60 VDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVF-ENFWQPDP 123
            .|  |||..|..::..||::.:|:|..|.|.:.||:.      :|...|..|..:. ...|.||.
Zfish    81 TD--IFVTSIGPVSDHDMEYTIDVFFRQSWKDERLKF------KGPMAVLRLNNLMASKIWTPDT 137

  Fly   124 YFLNSK--IAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSS 186
            :|.|.|  :|...|:.:|...:|  :..|:.|..|:.....|.|..:.:|||...||:...|::.
Zfish   138 FFHNGKKSVAHNMTMPNKLLRIT--EEGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAY 200

  Fly   187 NNQKVKLRW----------SDSGVTLNPELKLLQYNL-GQPLELEESDGYMPEKVGNFSRLTVYF 240
            ...:|...|          :|.|..||      ||:| ||.::    .|.:....|.:..:|.:|
Zfish   201 TRAEVVYVWTRGAAQSVVVADDGSRLN------QYDLMGQSVD----SGVVQSSTGEYVVMTTHF 255

  Fly   241 RFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAY 303
            ..:|:||:.:|||:.|..:.|:||..||||..:::|.|....||.:||:.|:...|  .:|.|||
Zfish   256 HLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAY 320

  Fly   304 VKALDLWMAGCMLSVFAALAEFVVVKVLDVQ-YQYQVNRIPKVLP----------MRISNMEKGQ 357
            ..|:|.::|.|...||:||.||..|.....: |.:...   .|:|          ::.:|.....
Zfish   321 ATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGK---SVVPEKQKKKKESLLKKNNTYTAA 382

  Fly   358 CAT-----VASWEGGAVRSRKATQTPTTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIM 417
            .||     :|...|.|..::.|...||.|.:     ...|..|..:::..||:
Zfish   383 TATAFAPNIARDPGLATIAKSAPPPPTEPKE-----EPKPKPPEAKKTFNSVS------------ 430

  Fly   418 WREIDKVSRAVFPILFFVFVLLYWPILLMK 447
              :||:::|..||:||..|.|:||...|.|
Zfish   431 --KIDRIARIAFPLLFGTFNLVYWATYLNK 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	128/477 (27%)
gabra1	XP_009293960.1	LIC	17..455	CDD:455710	129/479 (27%)
		LGIC_ECD_GABAAR_A1	67..260	CDD:349835	55/212 (26%)
		Cys-loop	177..191	CDD:349835	5/13 (38%)