DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12344 and Gabre

DIOPT Version :9

Sequence 1:	NP_001286298.1	Gene:	CG12344 / 36145	FlyBaseID:	FBgn0033558	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_075579.1	Gene:	Gabre / 65191	RGDID:	68320	Length:	989	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	128/481 - (26%)
Similarity:	201/481 - (41%)	Gaps:	88/481 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SEATEAHMNYTAKPRVVLP----------PNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDM 77
            :|.|..|.  |.:||..|.          .||..::| ||....|.:|...:||..:..|::.||
  Rat   537 TELTADHT--TERPRGKLTRASQILNTILSNYDHKLR-PSIGEKPTVVTVKVFVNSLGPISILDM 598

  Fly    78 DFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTS 142
            ::.:|:..:|.|.:.||.. :|.||.    :.|...|....|.||.:|.|||..:...:|.....
  Rat   599 EYSIDIIFYQTWYDERLRY-NDTFET----LILHGNVVSQLWIPDTFFRNSKRTQEYDITIPNQM 658

  Fly   143 VTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELK 207
            ..::|:..|.|..||.....|.:....:|||...||:...|||.:..::..:|.      |.:||
  Rat   659 ALIHKDGKVLYTVRMTIDARCSLHMLNFPMDSHSCPLSFSSFSYDEHEMIYKWE------NFKLK 717

  Fly   208 LLQYNLGQPLELE-----ESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFS 267
            :...|..:.||.:     .....:...||:|..:|.:|...|:.|..:.|.:.|||:..||||.|
  Rat   718 IDAKNTWKLLEFDFTGVNNKTEIISTPVGDFMVMTFFFNVSRRFGFIVFQNYIPSSVTTMLSWVS 782

  Fly   268 FWLGLDAIPGRVTLLVTCMLTLVTM--FTGADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKV 330
            ||:.::|...|.::.|:.:||:.|:  |:..:.|.|:|:.|||.::|.|.:..|..|.||.|:..
  Rat   783 FWIKIEAAAARASVGVSSVLTMATLGTFSRKNFPRVSYLTALDFYIAICFVLCFCTLLEFTVLNF 847

  Fly   331 LDVQ----------YQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTP------T 379
            |...          ||:..|       .|.:...:.:..|.|     ..|:|...|..      .
  Rat   848 LTYNNIERQASPKFYQFPTN-------SRANARTRARARTRA-----RARARARQQQEVFVCEIV 900

  Fly   380 TPGQTSLQGNGGPPKPARRQSLLSVAWTDTD----------------TGVEKIMWR--------- 419
            |..:.:.:|....|:..|.|    ..|....                .|.|...|:
  Rat   901 TYEENAEEGYQWSPRSRRPQ----CPWRRCGRSYVCFRVLRKYFCMVPGCEGNSWQRGRICIHVY 961

  Fly   420 EIDKVSRAVFPILFFVFVLLYWPILL 445
            .:|..||.:|||.||.|.::||.|.|
  Rat   962 RLDNYSRVLFPITFFFFNVVYWVICL 987

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	124/475 (26%)
Gabre	NP_075579.1	Neur_chan_LBD	555..760	CDD:280998	56/216 (26%)
		LIC	557..983	CDD:273305	117/453 (26%)
		Neur_chan_memb	769..983	CDD:280999	58/229 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010