Protein Alignment alka and gabrg3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_009300843.1
• Gene: gabrg3 / 567057
• ZFINID: ZDB-GENE-070718-5
• Length: 464
• Species: Danio rerio
• Alignment Length: 469
• Identity: 116/469 - (24%)
• Similarity: 192/469 - (40%)
• Gaps: 105/469 - (22%)

  Fly    23 SEATEAHMNYTAKPRVVLPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQ 87
            ::||:...|        |...|.|::||.... .|.::|..|:|..|..::..:|::::|:...|
Zfish    45 TDATQILNN--------LLKEYDKKLRPDIGV-KPTVIDVDIYVNSIGPVSSINMEYQIDIIFAQ 100

  Fly    88 RWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVR 152
            .|.:|||.     :......:||...:....|.||..|.|||.|:...:|.....:.::.:..:.
Zfish   101 TWTDSRLR-----YNSTMKILTLNSNMVGLIWLPDTIFRNSKSADSHWITTPNQLLRIWNDGKIL 160

  Fly   153 YAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTL--NPELKLLQYNLGQ 215
            |..|:.....||::...:|||...||:...|:.....::..:|..:.|..  ....:|.|::.
Zfish   161 YTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPRDEMIYKWRRNSVQAADQKSWRLYQFDF-- 223

  Fly   216 PLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVT 280
             :.|..:...:....|::..:||||...|::|:..|||:.|..|.|:|||.|||:..||.|.|..
Zfish   224 -MGLRNTTDVIKTTAGDYVVMTVYFDLSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTA 287

  Fly   281 LL-----------------VTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFV 326
            |:                 :|.:||:.|:.|.|  .:|.|:||.|:||::..|.|.|||||.|:.
Zfish   288 LVSCFKSMSCPGKCHCCQGITTVLTMTTLSTVARTSLPRVSYVTAMDLFVTVCFLFVFAALMEYA 352

  Fly   327 VVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTPTTPGQTSLQGNGG 391
            .:.    .|.|.                                :|:.|...|.....|:...|.
Zfish   353 TLN----YYSYS--------------------------------ARRPTCNKTKRSNYSVLDVGP 381

  Fly   392 PPKPARRQSLLSVAWTDTDTG-VEKIM-------------------WR---------EIDKVSRA 427
            ||......:  |:.|.:.|.. |.:.:                   ||         |:|..||.
Zfish   382 PPTVITLNN--SMYWQEFDDACVYECLDGKDCQSFFCCYEECKDGAWRKGRVHIDILELDAYSRV 444

  Fly   428 VFPILFFVFVLLYW 441
            .||..|.:|.::||
Zfish   445 FFPTSFLLFNVVYW 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	114/467 (24%)
gabrg3	XP_009300843.1	LIC	49..461	CDD:455710	114/465 (25%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	42/188 (22%)
		Cys-loop	171..185	CDD:349801	5/13 (38%)