Protein Alignment alka and gabra6b

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 437
• Identity: 119/437 - (27%)
• Similarity: 193/437 - (44%)
• Gaps: 71/437 - (16%)

  Fly    44 YVKEIRPPSKKGSPVI-VDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107
            |...:||..  |.||. |...|||.....::..:|::.:|:|..|.|::.||:     ||...:.
Zfish    42 YDNRLRPGF--GGPVTEVKTDIFVTSFGPVSDVEMEYTMDVFFRQTWIDDRLK-----FEGPIEI 99

  Fly   108 VTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTS----VTLYKNKTVRYAARMHAIIACQMEFQ 168
            :.|...:....|.||.:|.|.|    .:::|..|:    ..:.:|.|:.|..|:.....|.|...
Zfish   100 LRLNNLMVSKIWTPDTFFRNGK----RSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPMRLI 160

  Fly   169 LYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPEL-----KLLQYNL-GQPLELEESDGYMP 227
            .:|||...||:...|::....::...|. .|...:.|:     .||||:| ||.:..|.    :.
Zfish   161 NFPMDGHSCPLKFGSYAYPMSEIVYTWK-KGPLFSVEVPQESSSLLQYDLIGQTVSSER----LK 220

  Fly   228 EKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTM 292
            ...|.:..:||||..:|::|..||||:.|..:.|:|:..|||:..:::|.|....:|.:||:.|:
Zfish   221 SNTGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFGITTVLTMTTL 285

  Fly   293 FTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEK 355
            ...|  .:|.|:|..|:|.::|.|...||:||.||..|.....   .|.|:     .:|.:|:.:
Zfish   286 SISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFST---LQANK-----ELRRANIAR 342

  Fly   356 GQCATVASWEGG------------------AVRSRKATQTPTTPGQTSLQGNGGPPKPARRQSLL 402
            ...|..|:...|                  ::..|.||...:.|.|:.....|. ..||....:
Zfish   343 AAAAAAAARSDGEGVLNPLDPGGVLKKRMNSLSQRSATDRFSRPSQSDFHQQGS-AVPANNMLI- 405

  Fly   403 SVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILLMKSS 449
                   .|.:       |||.||.:||:.|..|.|:||.:.|.|.:
Zfish   406 -------GTSI-------IDKYSRILFPLSFGAFNLVYWIVYLTKDT 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	115/427 (27%)
gabra6b	XP_002667403.3	LIC	33..433	CDD:455710	117/430 (27%)
		LGIC_ECD_GABAAR_A6	41..238	CDD:349840	56/211 (27%)
		Cys-loop	155..169	CDD:349840	5/13 (38%)