Protein Alignment CG12344 and nAChRalpha2

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_524482.1
• Gene: nAChRalpha2 / 42919
• FlyBaseID: FBgn0000039
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 82/368 - (22%)
• Similarity: 156/368 - (42%)
• Gaps: 55/368 - (14%)

  Fly    18 ILMWLSEATEAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFR 80
            :|:.|.|..:|  |..|| |:.  |..||.:.|||.|.....|:|...:.:..:..:|::|....
  Fly    31 VLLLLCETVQA--NPDAK-RLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILT 92

  Fly    81 VDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAE--IATLTHKFTSV 143
            .::::...|.:.:.:.  |..|.|.  ||.|....|:.|.||....|:...|  :.|:|   .::
  Fly    93 TNVWLEHEWQDHKFKW--DPSEYGG--VTELYVPSEHIWLPDIVLYNNADGEYVVTTMT---KAI 150

  Fly   144 TLYKNKTVRYAARMHAII--ACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW------SDSGV 200
            ..|..|.|....   ||.  :|:::.:.:|.|.|.|.:...|::.:..::.|:.      .|:.|
  Fly   151 LHYTGKVVWTPP---AIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKV 212

  Fly   201 TLNPELKLLQYN-------LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSS 258
            .:..:|:  :|.       ||.|.|..|.  |.|.....:..:.......|:...:.:....|..
  Fly   213 EIGIDLR--EYYPSVEWDILGVPAERHEK--YYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCV 273

  Fly   259 LVVMLSWFSFWLGLDAIPGRVTLLVTCML--TLVTMFTGADIPPVAY-VKALDLWMAGCMLSVFA 320
            .:..||...|:|..|: ..::.|.::.:|  |:..:.....||..:. :..|..::...||.|
  Fly   274 GISYLSVLVFYLPADS-GEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLV-- 335

  Fly   321 ALAEFVVVKVLDVQYQ-------------YQVNRIPKVLPMRI 350
            .|:..:.:.:|::.|:             :.:.|:||:|.||:
  Fly   336 GLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRV 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	82/368 (22%)
nAChRalpha2	NP_524482.1	LGIC_ECD_nAChR_proto_alpha-like	44..263	CDD:349832	53/233 (23%)
		LIC	47..544	CDD:273305	75/349 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100