Protein Alignment CG12344 and Grd

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_524131.1
• Gene: Grd / 39984
• FlyBaseID: FBgn0001134
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 142/591 - (24%)
• Similarity: 219/591 - (37%)
• Gaps: 176/591 - (29%)

  Fly    21 WLSEATEAHMNYTAKPRVVLPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFI 85
            ||:::.. |.|.:.....:| ..|...|| |...|.|..::..|.|..:..|:..||.:.:|.:.
  Fly    99 WLTQSNN-HANISELLDNLL-RGYDNSIR-PDFGGPPATIEVDIMVRSMGPISEVDMTYSMDCYF 160

  Fly    86 HQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKT 150
            .|.|::.||     .||...|.:.|...:....|:||.||.|.|.:.:.|:|.....|.:|:|..
  Fly   161 RQSWVDKRL-----AFEGAQDTLALSVSMLARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGR 220

  Fly   151 VRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDS--GVTLNPELKLLQYNL 213
            |.|::|:.....|.|....:|||||.||:...||......|..||:..  .|.:..::||.|::|
  Fly   221 VLYSSRLTIKAGCPMNLADFPMDIQKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDL 285

  Fly   214 ----------------------------------------------------GQPLELE------ 220
                                                                |..|:|:
  Fly   286 VDCPAGNLTDIVYKAAAPRPQRRPFNNKDPPRPTSKVMTTFAGPAAKNQHVRGTGLKLDKGAFGT 350

  Fly   221 --ESDGYMPEKVG-------------NFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 270
              ::.|......|             .:|.|.|.|..:|.:|:.|||.:.|..|:|:|||.||||
  Fly   351 GRDATGGSGSTTGLSGTITLETNHPSEYSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWL 415

  Fly   271 GLDAIPGRVTLLVTCMLTLVTMFTG----ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVV--- 328
            ..:|...||:|.:|.:||:.  |.|    .|:|.|:|..|||.::......:||.:.:|.||
  Fly   416 NREATADRVSLGITTVLTMT--FLGLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYY 478

  Fly   329 ------------KVLDVQYQYQ-------------VNRIPKVLPM-------------------- 348
                        :.||.:....             .::|.:|:|:
  Fly   479 TKYGSGECYFIIEELDSESGESETEPLTSDFRGSTESKIYEVIPLSMCAISMPPPPTRLGMLTSR 543

  Fly   349 --RISNMEKG----QCATVASWEGGAVRSRKATQTPTTPG----QTSLQGNGGP---PKPARRQS 400
              |..|...|    :...:..|.    |.||..:..:...    ||.|:.|..|   ...|..|:
  Fly   544 NRRPRNRRHGLWSMKLLGLFDWR----RRRKPPRADSDEDEDDEQTQLRANEAPTTSAAAAAAQA 604

  Fly   401 LLSVAWTDTDTGVEKIM--WR--------------------EIDKVSRAVFPILFFVFVLLYWPI 443
            ....|.....||..:.|  :|                    :||:.||.|||:||.:..:.||..
  Fly   605 AAQAARISPPTGGRRRMSYYRREEMEARRKGKRTPQYNSVSKIDRASRIVFPLLFILINVFYWYG 669

  Fly   444 LLMKSS 449
            .|.:||
  Fly   670 YLSRSS 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	137/581 (24%)
Grd	NP_524131.1	Neur_chan_LBD	110..326	CDD:280998	55/222 (25%)
		LIC	111..670	CDD:273305	135/571 (24%)
		Neur_chan_memb	398..667	CDD:280999	64/274 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920