Protein Alignment CG12344 and lgc-38

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001355511.1
• Gene: lgc-38 / 3565717
• WormBaseID: WBGene00017389
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 435
• Identity: 125/435 - (28%)
• Similarity: 215/435 - (49%)
• Gaps: 65/435 - (14%)

  Fly    46 KEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTL 110
            :.|| |:..|.|:.|:.:..|..|::::...||:.:|:::.|.|.:.||....|:    :|.:|:
 Worm    65 RRIR-PNYGGPPIEVNITAHVTTISAVSEVSMDYTLDLYLRQIWKDPRLAWESDV----EDSLTI 124

  Fly   111 LPEVFENFWQPDPYFLNSKIAEIATLTHKFTS----VTLYKNKTVRYAARMHAIIACQMEFQLYP 171
            ..::.:..|.||.:|.|.|    .:..|:.||    :.:..:..|..:.|:.....|.|....:|
 Worm   125 GIDMVKTIWTPDTFFPNEK----KSFFHEATSHNSFLRIDNHGNVLRSIRLTVTANCPMSLHTFP 185

  Fly   172 MDIQVCPIYIESFSSNNQKVKLRW-SDSGVTLNPELKLLQYNLGQPLELEESDGYMPEKVGNFSR 235
            :|.|.|.:.:||:..:.:.:...| ..:.||::..:.|..:.:|:...:|.:   :....||:||
 Worm   186 LDRQECALEVESYGYSTKDIIYHWHGTNAVTIDENVHLAHFTIGEHKHIERT---ISLSTGNYSR 247

  Fly   236 LTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMF--TGADI 298
            ||.||.|:|.||.:|||.:.||||:|::||.||||..:|:..||.:.||.:||:.|:.  |.|.:
 Worm   248 LTAYFLFKRNIGFYLIQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVLTMTTLMTSTNASL 312

  Fly   299 PPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNR-IPKVLPMRISNMEKG---QCA 359
            |.|:|||:||:::..|...|||:|.|:..     :.|..:.|| :|...|::....|:.   ||.
 Worm   313 PKVSYVKSLDVFLGVCFFIVFASLLEYAA-----IGYLMKRNRSVPAASPVQYYETEEFFEIQCH 372

  Fly   360 TVASWEGGAVR----------SRKATQTPTTPGQTSLQGNGGPPKPA-----RRQSLLSV----- 404
              ..:..||:.          |||.::........:.|.|....:|:     :|..|||:
 Worm   373 --PKFVRGAINYCDGVLKREASRKKSRNRRDSSMKNYQNNNIHHRPSDGHVDQRIPLLSMVPMPP 435

  Fly   405 --------AWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYW 441
                    ||       .|:...::|..||..|||.|.:|.::||
 Worm   436 IPFKPQNGAW-------GKVRPAQVDLFSRFAFPIFFVIFHIVYW 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	123/433 (28%)
lgc-38	NP_001355511.1	LIC	42..476	CDD:273305	125/435 (29%)
		LGIC_ECD_GABAR_RDL-like	76..257	CDD:349809	47/191 (25%)
		Cys-loop	177..191	CDD:349809	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810