Protein Alignment alka and lgc-36

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001023766.1
• Gene: lgc-36 / 3565335
• WormBaseID: WBGene00008551
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 468
• Identity: 104/468 - (22%)
• Similarity: 201/468 - (42%)
• Gaps: 91/468 - (19%)

  Fly    43 NYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107
            ||.:..||....|.|..|...:|:..:..::.....:..:.:..|:|.:.||...:...  |...
 Worm    72 NYDQHFRPGFNSGKPTKVYIDLFIRTMGPVSDLFNTYSFNCYFRQKWTDDRLHFNNSGI--GFRQ 134

  Fly   108 VTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPM 172
            ::|...:.:..|:||.||.|...:.:..:|.....|.|..:.|:.|::|:.....|||:...||:
 Worm   135 LSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGTILYSSRITVKAKCQMDMSRYPL 199

  Fly   173 DIQVCPIYIESFSSNNQKVKLRW----SDSGVTLN-------PELKLLQYNLGQPLELEESDGYM 226
            |.|.|.:.|.|::.::.:|:.:|    .|:||.::       |:..|..:.:.:|..:.....|
 Worm   200 DKQACRLVIGSYAYSSDEVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPANITRDKEY- 263

  Fly   227 PEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLT--L 289
                   |.|.|.|.|:|..|:.|:..:.|.:|||:|.|.:|:...:|...|:.:.:|.:||  |
 Worm   264 -------SALEVRFYFDRHFGYFLMNFYVPCALVVLLCWVAFFTKREATAERIGIGITNVLTIVL 321

  Fly   290 VTMFTGADIPPVAYVKALDLWMAGCMLSVFAALAEFVVV-----------KVLDVQYQYQVNRIP 343
            ::|.:.:|.|.|....||::::..|.|:....:.||.||           ::.:|:.: ::.:|.
 Worm   322 ISMDSKSDSPKVDSPTALEVFIWICYLTHLICMVEFTVVHYHTKYNTGDPEIQEVERE-RLRQII 385

  Fly   344 KVLPMRISNMEKGQCATVASWEGGAVRSRKATQTPTT-----PGQTSLQGNGGPPKPARR----- 398
            |.:|...:|.     ||..::.      |:....|.:     |.:|....:...||.:.:
 Worm   386 KQIPKNTNNR-----ATEPTFR------RRNAALPVSIARPLPNKTKRFMSVRQPKKSEQTESIQ 439

  Fly   399 -----QSLLSVAWTDTDTGV-------EKIMWR-----------------------EIDKVSRAV 428
                 .::.|....:.::.:       |.:.||                       .|||:|..|
 Worm   440 LMRKISNMESTTHNEVESSLNLESIRQENVGWRLYYWMIDHNIKTDPFGVAQNSTSRIDKISVIV 504

  Fly   429 FPILFFVFVLLYW 441
            .|::|.:.:.||:
 Worm   505 APLIFILTIALYY 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	103/466 (22%)
lgc-36	NP_001023766.1	LIC	48..520	CDD:455710	104/468 (22%)
		LGIC_ECD_GABAR_GRD-like	86..275	CDD:349808	45/198 (23%)
		Cys-loop	190..204	CDD:349808	7/13 (54%)