Protein Alignment alka and nAChRbeta3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 95/478 - (19%)
• Similarity: 170/478 - (35%)
• Gaps: 118/478 - (24%)

  Fly    15 LGFILMWLSEATEAHMNYTAKPR-----------VVLPPNYVKEIRPPSKKGSPVIVDFSIFV-- 66
            :|.:||.|:....|  ..||.|:           ..|..||..:::|.. :|:|..|...:.|
  Fly    24 MGMLLMGLTSVPGA--TATADPKNANVKALDRLHAGLFTNYDSDVQPVF-QGTPTNVSLEMVVTY 85

  Fly    67 VDINSINVEDMDFRVDMFIHQRWL-ESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSK- 129
            :||:.:|.:   .....:::.||. |.|:..|...     |.:|.:.......|.|.....|..
  Fly    86 IDIDELNGK---LTTHCWLNLRWRDEERVWQPSQY-----DNITQITLKSSEVWTPQITLFNGDE 142

  Fly   130 ---IAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKV 191
               :||        |.|||..:...|:.........|::....:|.|.|.|.:.|.|:.     :
  Fly   143 GGLMAE--------TQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSWG-----L 194

  Fly   192 KLRWSDSGVTLNPELKLLQYNLGQPLELEESD-----------GYMPEKVGNFSRLTVYFRFERQ 245
            |:...::|......|.  ..:|.|..|.|..|           |||.      ..||.    :|:
  Fly   195 KVVLPENGTARGESLD--HDDLVQSPEWEIVDSRAHFVSQDYYGYME------YTLTA----QRR 247

  Fly   246 IGHHLIQTFAPSSLVVMLSWFSFWLGLDAIP---GRVTLLVTCMLTLV----TMFTGADIPPVAY 303
            ...:....:.|:|.:|:|:..:|||     |   |...:::..:|.:|    .|:....:|.::.
  Fly   248 SSMYTAVIYTPASCIVILALSAFWL-----PPHMGGEKIMINGLLIIVIAAFLMYFAQLLPVLSN 307

  Fly   304 VKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASW---- 364
            ...|.:......| ::.:::..|.|.||.:.......|:|:.|    ..:..|...|   |
  Fly   308 NTPLVVIFYSTSL-LYLSVSTIVEVLVLYLATGKHKRRLPEAL----RKLLHGHLGT---WLLLS 364

  Fly   365 ---EGGAVRSRKATQTPTTPGQTSLQGNGGP--------PKPARRQ---SLLSVAWTDTDTGVEK 415
               ..|..::.|..:....|.:.:.:....|        |.....|   :||:.|
  Fly   365 VFSTTGESQAEKTKEMDEHPYEEADEQESSPLGINHTEVPGAKANQFDWALLATA---------- 419

  Fly   416 IMWREIDKVSRAVFPILFFVFVL 438
                 :|::|...|.:.|.:..:
  Fly   420 -----VDRISFVSFSLAFLILAI 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	95/478 (20%)
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:455710	90/459 (20%)