Protein Alignment CG12344 and nAChRalpha7

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001162795.1
• Gene: nAChRalpha7 / 32928
• FlyBaseID: FBgn0086778
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 93/422 - (22%)
• Similarity: 159/422 - (37%)
• Gaps: 77/422 - (18%)

  Fly     6 NTNAFISFGLGFILMWLSEATEAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVIVDFSIFVVD 68
            |....:.:|||.::|..:.|...|     :.|::  |..||....||...:..|:.:.|.:.::.
  Fly    37 NGGRMLVYGLGLLIMIPACAAGPH-----EKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQ 96

  Fly    69 INSINVEDMDFRVDMFIHQRWLESRLEIPD-----DIFEEGDDYVTLLPEVFENFWQPDPYFLNS 128
            |     .|:|.:..:.|...||  :||..|     :..|.|......:|.  ...|:||....||
  Fly    97 I-----IDVDEKNQLLITNIWL--KLEWNDMNLRWNSSEFGGVRDLRIPP--HRLWKPDVLMYNS 152

  Fly   129 KIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKL 193
              |:........|:|.:..|.:..|.........|:::...:|.|.|.|.:...|::.:..::.|
  Fly   153 --ADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDL 215

  Fly   194 RWSD------SGVTLNPELKLLQYNLGQPLELEESDGY---MPEKVGNFSRLTVYFRFERQIGHH 249
            :..|      |....|.|..|    ||.|.:..|.  |   .||.   :..:|......|:..::
  Fly   216 QLQDEAGGDISSFITNGEWDL----LGVPGKRNEI--YYNCCPEP---YIDITFAILIRRKTLYY 271

  Fly   250 LIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLV--------TMFTGADIPPVAYVKA 306
            ......|..|:..::...|.|..|: ..:::|.||.:|:|.        ||...:|..|:
  Fly   272 FFNLIVPCVLIASMALLGFTLPPDS-GEKLSLGVTILLSLTVFLNMVAETMPATSDAVPL----- 330

  Fly   307 LDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRS 371
            |..:. .|::.:   :|..||..:|.:.|.:   |.|..     ..|.:........|....:|.
  Fly   331 LGTYF-NCIMFM---VASSVVSTILILNYHH---RNPDT-----HEMSEWIRVIFLYWLPCILRM 383

  Fly   372 RKATQTPTTPGQTSLQGNGGPPKPARRQSLLS 403
            ::       |||.   |...||.|:...|..|
  Fly   384 QR-------PGQV---GYECPPPPSSSSSSAS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	92/420 (22%)
nAChRalpha7	NP_001162795.1	LIC	59..548	CDD:273305	87/400 (22%)
		Neur_chan_LBD	61..268	CDD:280998	51/226 (23%)
		Neur_chan_memb	275..552	CDD:280999	35/159 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100