Protein Alignment alka and CG8916

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 127/494 - (25%)
• Similarity: 200/494 - (40%)
• Gaps: 113/494 - (22%)

  Fly    44 YVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYV 108
            |.:...|...:|.|.:|..:|.:..:..::..|||:.:|.:..|.|.:.||.....|     ..:
  Fly   119 YEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPI-----KSL 178

  Fly   109 TLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMD 173
            :|..::.:..|:||.||.|.|.::|..:|.....:.|.:|..:.|:.|:.....|.||.|.:|||
  Fly   179 SLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMD 243

  Fly   174 IQVCPIYIESFSSNNQKVKLRW--SDSGVTLNPELKLLQYNLGQPLELEESDGYMPEKVGNFSRL 236
            .|.||:.|.|:...||::...|  .|..|:..|.:.|.|::|   :.:...:.....:.|:||.|
  Fly   244 RQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDL---ISMMHRNFTTVRREGDFSVL 305

  Fly   237 TVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTL--VTMFTGADIP 299
            .|.|..:|..|:.|||.:.|..|:|:|||.|||:..:|...||:|.||.:|||  :::.:..|:|
  Fly   306 HVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLP 370

  Fly   300 PVAYVKALDLWMAGCMLSVFAALAEFVVVKVL---------DVQYQYQVNRIPKVLPMRISNM-- 353
            .|.|..|||.::....|...|.|.||..|...         .::.|::...|...|......:
  Fly   371 KVKYATALDWFLLMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDG 435

  Fly   354 -----------------------EKGQCATVASWEGGAVRSRKATQTPTTPG-------QTSLQG 388
                                   |.|...:|.|..|..|.::.     ...|       |.||.|
  Fly   436 DGEADADPFADEDSSNGSENDDNEAGASESVESKSGVCVCNKN-----DALGLEYEVSLQNSLAG 495

  Fly   389 NGGPPKPARRQSLLSVAWTD------------TDT---GVEKI--MW------------RE---- 420
            .|.    .:|.::....:.|            |.|   .|.::  ||            ||
  Fly   496 AGF----LKRNAIFCPTYNDPSYILPNTMERTTQTEPPAVSRLHQMWMCLKSDNSFRKQRERNAA 556

  Fly   421 ------------------IDKVSRAVFPILFFVFVLLYW 441
                              ||:|:|..||:.|....||||
  Fly   557 AQKSEQGGANCYVNSVSLIDRVARIAFPMSFAFLNLLYW 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	125/492 (25%)
CG8916	NP_573090.3	LIC	92..598	CDD:455710	127/494 (26%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	53/189 (28%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)