Protein Alignment alka and Gabrg2

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001380704.1
• Gene: Gabrg2 / 29709
• RGDID: 61966
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 117/466 - (25%)
• Similarity: 209/466 - (44%)
• Gaps: 63/466 - (13%)

  Fly    17 FILMWLS--------EATEAHMNYTAKPRVVLPP----------------NYVKEIRPPSKKGSP 57
            :||:.||        ::.:.:.:|.:....||.|                .|..::||.... .|
  Rat    25 WILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGV-KP 88

  Fly    58 VIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPD 122
            .::...::|..|..:|..:|::.:|:|..|.|.:.||:     |......:.|...:....|.||
  Rat    89 TLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLK-----FNSTIKVLRLNSNMVGKIWIPD 148

  Fly   123 PYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSN 187
            .:|.|||.|:...:|.....:.::.:..|.|..|:.....||::...:|||...||:...|:...
  Rat   149 TFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYP 213

  Fly   188 NQKVKLRWSDSGVTLNP--ELKLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHL 250
            .:::..:|..|.|.:..  ..:|.|::.   :.|..:...:....|::..::|||...|::|:..
  Rat   214 REEIVYQWKRSSVEVGDTRSWRLYQFSF---VGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFT 275

  Fly   251 IQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAG 313
            |||:.|.:|:|:|||.|||:..||:|.|.:|.:|.:||:.|:.|.|  .:|.|:||.|:||:::.
  Rat   276 IQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSV 340

  Fly   314 CMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTP 378
            |.:.||:||.|:..:      :.:..||.|.   ......:|.....:.|::...:..|..:.|.
  Rat   341 CFIFVFSALVEYGTL------HYFVSNRKPS---KDKDKKKKNPLLRMFSFKAPTIDIRPRSATI 396

  Fly   379 TTPGQTSLQGN----GGPPKPARRQSLLSVAWTDTDTGVEKIMWR---------EIDKVSRAVFP 430
            .....|.||..    |......:..:.....:.|..||.    ||         ::|..:|..||
  Rat   397 QMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGA----WRHGRIHIRIAKMDSYARIFFP 457

  Fly   431 ILFFVFVLLYW 441
            ..|.:|.|:||
  Rat   458 TAFCLFNLVYW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	115/464 (25%)
Gabrg2	NP_001380704.1	LIC	68..471	CDD:455710	109/423 (26%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	42/188 (22%)
		Cys-loop	189..203	CDD:349801	5/13 (38%)