DRSC/TRiP Functional Genomics Resources

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Protein Alignment alka and Gabra6

DIOPT Version :10

Sequence 1:NP_610619.2 Gene:alka / 36145 FlyBaseID:FBgn0033558 Length:449 Species:Drosophila melanogaster
Sequence 2:NP_068613.2 Gene:Gabra6 / 29708 RGDID:61861 Length:453 Species:Rattus norvegicus


Alignment Length:482 Identity:128/482 - (26%)
Similarity:203/482 - (42%) Gaps:94/482 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 FILMWLSEA---TEAHMNYTAK--PRVV--LPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINV 74
            |.|:|:..|   .|...|:.::  .|::  |...|...:| |...|:...|...|:|.....::.
  Rat     9 FSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLR-PGFGGAVTEVKTDIYVTSFGPVSD 72

  Fly    75 EDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHK 139
            .:|::.:|:|..|.|.:.||:     |:...:.::|...:....|.||.:|.|.|    .::.|.
  Rat    73 VEMEYTMDVFFRQTWTDERLK-----FKGPAEILSLNNLMVSKIWTPDTFFQNGK----KSIAHN 128

  Fly   140 FTS----VTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGV 200
            .|:    ..|.:|.|:.|..|:.....|.|....:|||...||:...|::....::...|. .|.
  Rat   129 MTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWK-KGP 192

  Fly   201 TLNPEL-----KLLQYNL-GQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSL 259
            ..:.|:     .||||:| ||.:..|.    :....|.:..:||||..:|::|:.:||.:.|..:
  Rat   193 LYSVEVPEESSSLLQYDLIGQTVSSET----IKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIM 253

  Fly   260 VVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAAL 322
            .|:||..|||:..:::|.|....:|.:||:.|:...|  .:|.|:|..|:|.::|.|...||:||
  Rat   254 TVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSAL 318

  Fly   323 AEFVVVKVL------DVQYQYQVNRIPKV----------------------LPMRISNMEKGQCA 359
            .||..|...      ..:.|.|....|.|                      |..|||::   ...
  Rat   319 IEFAAVNYFTNLQSQKAERQAQTAAKPPVAKSKTTESLEAEIVVHSDSKYHLKKRISSL---TLP 380

  Fly   360 TVASWEGGAVRSRK--ATQTPTTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREID 422
            .|.|.|...|.||.  ...||.|| ...|...||..|                          ||
  Rat   381 IVPSSEASKVLSRTPILPSTPVTP-PLLLPAIGGTSK--------------------------ID 418

  Fly   423 KVSRAVFPILFFVFVLLYWPILLMKSS 449
            :.||.:||:.|..|.|:||.:.|.|.:
  Rat   419 QYSRILFPVAFAGFNLVYWIVYLSKDT 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alkaNP_610619.2 LIC 8..441 CDD:455710 124/472 (26%)
Gabra6NP_068613.2 LIC 34..440 CDD:455710 120/450 (27%)
LGIC_ECD 42..239 CDD:475126 53/211 (25%)

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