Protein Alignment CG12344 and Gabra1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_899155.1
• Gene: Gabra1 / 29705
• RGDID: 61855
• Length: 455
• Species: Rattus norvegicus
• Alignment Length: 441
• Identity: 124/441 - (28%)
• Similarity: 202/441 - (45%)
• Gaps: 61/441 - (13%)

  Fly    31 NYTAKPRVV--LPPNYVKEIRPP-SKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLES 92
            |.|...|::  |...|...:||. .::.:.|..|  |||.....::..||::.:|:|..|.|.:.
  Rat    37 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTD--IFVTSFGPVSDHDMEYTIDVFFRQSWKDE 99

  Fly    93 RLEIPDDIFEEGDDYVTLLPEVF-ENFWQPDPYFLNSK--IAEIATLTHKFTSVTLYKNKTVRYA 154
            ||:.      :|...|..|..:. ...|.||.:|.|.|  :|...|:.:|...:|  ::.|:.|.
  Rat   100 RLKF------KGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT--EDGTLLYT 156

  Fly   155 ARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW----SDSGVTLNPELKLLQYN-LG 214
            .|:.....|.|..:.:|||...||:...|::....:|...|    :.|.|......:|.||: ||
  Rat   157 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 221

  Fly   215 QPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRV 279
            |.::    .|.:....|.:..:|.:|..:|:||:.:|||:.|..:.|:||..||||..:::|.|.
  Rat   222 QTVD----SGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 282

  Fly   280 TLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQ-YQYQVNR 341
            ...||.:||:.|:...|  .:|.|||..|:|.::|.|...||:||.||..|.....: |.:....
  Rat   283 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKS 347

  Fly   342 IPKVLPMRISN--MEKGQ--CATVASW--------EGGAVRSRKATQTPTTPGQTSLQGNGGPPK 394
            :....|.::.:  ::|..  ..|..|:        .|.|..::.||..|     ..::....||:
  Rat   348 VVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEP-----KEVKPETKPPE 407

  Fly   395 PARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILL 445
            |.:           |...|.|     ||::||..||:||.:|.|:||...|
  Rat   408 PKK-----------TFNSVSK-----IDRLSRIAFPLLFGIFNLVYWATYL 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	121/435 (28%)
Gabra1	NP_899155.1	LIC	7..441	CDD:273305	123/438 (28%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	53/206 (26%)
		Cys-loop	165..179	CDD:349835	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820