Protein Alignment alka and Gabrr2

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_038965308.1
• Gene: Gabrr2 / 29695
• RGDID: 61902
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 121/449 - (26%)
• Similarity: 210/449 - (46%)
• Gaps: 75/449 - (16%)

  Fly    33 TAKPRVVL-PPNYVKEIRPPSKKGSPVI-VDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLE 95
            |.|||.:| ..::...:||..  |.|.| |...:.|..::||:..||||.:.:::...|.:.||.
  Rat    78 TGKPRPLLRVEDHDFTMRPAF--GGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWRDERLA 140

  Fly    96 IPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTS----VTLYKNKTVRYAAR 156
            .|    ...:..:|....:.:..|.||.:|::||    .:.||..|:    :.::.:..|.|:.|
  Rat   141 FP----SSSNRSMTFDGRLVKKIWVPDVFFVHSK----RSFTHDTTTDNIMLRVFPDGHVLYSMR 197

  Fly   157 MHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELK------LLQ-YNLG 214
            :.....|.|:|..:|:|.|.|.:.:||::..::.:.|.|.:...:|..:.|      |:| ::..
  Rat   198 ITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTT 262

  Fly   215 QPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRV 279
            ..|....|.|:       ::||.:.|...|.|...|:||:.|::|:|||||.|||:...|:|.||
  Rat   263 SRLAFYSSTGW-------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARV 320

  Fly   280 TLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRI 342
            :|.:..:||:.|:.||  |.:|.|:|::|:|:::....:.||.::.|:..|..|....:.:..::
  Rat   321 SLGIMTVLTMSTIITGVNASMPRVSYIRAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQEQKERKL 385

  Fly   343 PKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTPTTPGQTS-LQGN---GGP-----PKPARR 398
                      .:|..|..      |.:.||    |.|..|..| .:.|   |.|     |:..|:
  Rat   386 ----------RDKFPCTC------GMLHSR----TMTLDGSYSESEANSLAGYPRSHILPEEERQ 430

  Fly   399 QSLL------SVAWTDTDTGVEKIMW--------REIDKVSRAVFPILFFVFVLLYWPI 443
            ..::      |...:....|:.|...        ..|||.||.:||..:.||.|:||.:
  Rat   431 DKIVVHLALNSELTSSRKKGLLKGQMGLYIFQNTHAIDKYSRLIFPAFYIVFNLIYWSV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	119/445 (27%)
Gabrr2	XP_038965308.1	LIC	87..490	CDD:455710	116/440 (26%)
		LGIC_ECD_GABAAR_rho	102..287	CDD:349806	48/199 (24%)
		Cys-loop	204..218	CDD:349806	6/13 (46%)