Protein Alignment alka and Gabrr1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_058987.3
• Gene: Gabrr1 / 29694
• RGDID: 61900
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 131/514 - (25%)
• Similarity: 221/514 - (42%)
• Gaps: 123/514 - (23%)

  Fly    11 ISFGLGFILMW---LSEATEAHMNYTAKPRVVLPPNYVKEIRPPSKK------------------ 54
            :.||: |:|.|   |:..:..|.           |.  :|:..||||
  Rat     7 MKFGI-FLLWWGWVLAAESTVHW-----------PG--REVHEPSKKGSRPQRQRRGAHDDAHKQ 57

  Fly    55 GSPVIV----------------------DFS---------------IFVVDINSINVEDMDFRVD 82
            |||::.                      |||               :.|..::||:..||||.:.
  Rat    58 GSPILKRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 122

  Fly    83 MFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYK 147
            :::...|.:.||..|    ...:..:|....:.:..|.||.:|::||.:.|...|.....:.:..
  Rat   123 LYLRHYWKDERLSFP----STNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQP 183

  Fly   148 NKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW--------SDSGVTLNP 204
            :..|.|:.|:.....|.|:|..:|:|.|.|.:.|||::.....:.|.|        :|..::|:
  Rat   184 DGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS- 247

  Fly   205 ELKLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 269
            :..:.:::....|....|.|:       ::||.:.|...|.|...|:||:.|::|:|||||.|||
  Rat   248 QFLIQEFHTTTKLAFYSSTGW-------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFW 305

  Fly   270 LGLDAIPGRVTLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVL- 331
            :...|:|.||.|.:|.:||:.|:.||  |.:|.|:|:||:|:::....:.||.::.|:..|..|
  Rat   306 IDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT 370

  Fly   332 DVQYQYQVNRIPKV-----LP-----MRISNMEKGQCATVASW--EGGAVRSRKATQTPTTPGQT 384
            .||.:.:.....|:     ||     |..|:...|:...:..:  |.|....|...|.      |
  Rat   371 TVQERKERKLREKISCTCGLPQPRGVMLDSSYSDGEVNDLGGYMPENGEKPDRMMVQL------T 429

  Fly   385 SLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPI 443
            .....|.|.:.::|.|.:|:          :|....|||.||.:||..:.:|.|:||.|
  Rat   430 LASERGSPQRKSQRGSYVSM----------RINTHAIDKYSRIIFPAAYILFNLIYWSI 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	128/510 (25%)
Gabrr1	NP_058987.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..67		8/35 (23%)
		LIC	76..479	CDD:455710	115/431 (27%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	44/196 (22%)
		Cys-loop	199..213	CDD:349806	6/13 (46%)