Protein Alignment alka and Gabrd

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_058985.1
• Gene: Gabrd / 29689
• RGDID: 61901
• Length: 449
• Species: Rattus norvegicus
• Alignment Length: 424
• Identity: 116/424 - (27%)
• Similarity: 201/424 - (47%)
• Gaps: 38/424 - (8%)

  Fly    40 LPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEG 104
            |...|.:..| |...|.||.|..::.|..|:.|:..:|::.:.:|:||.|.:|||.     :...
  Rat    47 LMEGYARNFR-PGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLS-----YNHT 105

  Fly   105 DDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQL 169
            ::.:.|.....:..|.||.:.:|:|.|....:|.:...:.|..:..:.|:.|:.:.:||.|:...
  Rat   106 NETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAK 170

  Fly   170 YPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLN--PELKLLQYNLGQPLELEESDGYMPEKVGN 232
            ||||.|.|.:.:||:..:::.:...||::...::  ..|:|.|:.:.......|...:  :..|.
  Rat   171 YPMDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNF--KSAGQ 233

  Fly   233 FSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA- 296
            |.||:::|:..|..|.::||::.||.|:|.:||.|||:...|:|.||:|.:|.:||:.|:...|
  Rat   234 FPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSAR 298

  Fly   297 -DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCAT 360
             .:|..:.:||||::...|.:.|||||.|:.... .:..|:.:.....||...| :.|:......
  Rat   299 SSLPRASAIKALDVYFWICYVFVFAALVEYAFAH-FNADYRKKRKAKVKVTKPR-AEMDVRNAIV 361

  Fly   361 VASWEGGAVR-----SRKATQTP--------TTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTG 412
            :.|.....|.     ||:..:.|        :...:...:|...|..|...:|.|..  .|.||
  Rat   362 LFSLSAAGVSQELAISRRQGRVPGNLMGSYRSVEVEAKKEGGSRPGGPGGIRSRLKP--IDADT- 423

  Fly   413 VEKIMWREIDKVSRAVFPILFFVFVLLYWPILLM 446
                    ||..:|||||..|....::||....|
  Rat   424 --------IDIYARAVFPAAFAAVNIIYWAAYTM 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	113/417 (27%)
Gabrd	NP_058985.1	LGIC_ECD	63..246	CDD:475126	47/189 (25%)
		LGIC_TM	249..>337	CDD:476813	33/88 (38%)
		TM1 helix	252..272	CDD:349850	11/19 (58%)
		TM2 helix	281..302	CDD:349850	6/20 (30%)
		TM3 helix	312..334	CDD:349850	7/22 (32%)