Protein Alignment CG12344 and GABRR1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_002033.2
• Gene: GABRR1 / 2569
• HGNCID: 4090
• Length: 479
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 127/509 - (24%)
• Similarity: 221/509 - (43%)
• Gaps: 118/509 - (23%)

  Fly    13 FGLGFILMW-LSEATEAHMNYTAKPRVVLPPNYVKEIRPPSKKG-----------------SPVI 59
            ||: |:|.| ...|||:.|::..           :|:...||||                 ||::
Human     9 FGI-FLLWWGWVLATESRMHWPG-----------REVHEMSKKGRPQRQRREVHEDAHKQVSPIL 61

  Fly    60 ----------------------VDFS---------------IFVVDINSINVEDMDFRVDMFIHQ 87
                                  .|||               :.|..::||:..||||.:.:::..
Human    62 RRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 126

  Fly    88 RWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVR 152
            .|.:.||..|    ...:..:|....:.:..|.||.:|::||.:.|...|.....:.:..:..|.
Human   127 YWKDERLSFP----STNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVL 187

  Fly   153 YAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW--------SDSGVTLNPELKLL 209
            |:.|:.....|.|:|..:|:|.|.|.:.|||::.....:.|.|        :|..::|: :..:.
Human   188 YSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLS-QFLIQ 251

  Fly   210 QYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDA 274
            :::....|....|.|:       ::||.:.|...|.|...|:||:.|::|:|||||.|||:...|
Human   252 EFHTTTKLAFYSSTGW-------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRA 309

  Fly   275 IPGRVTLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQY 337
            :|.||.|.:|.:||:.|:.||  |.:|.|:|:||:|:::....:.||.::.|:..|..|....:.
Human   310 VPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQER 374

  Fly   338 QVNRIPKVLP-----------MRISNMEKGQCATVASW--EGGAVRSRKATQTPTTPGQTSLQGN 389
            :..::.:.||           |...|...|:...:.::  |.|....|...|......::|
Human   375 KEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSS---- 435

  Fly   390 GGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPI 443
              |.:.::|.|.:|:          :|....|||.||.:||..:.:|.|:||.|
Human   436 --PQRKSQRSSYVSM----------RIDTHAIDKYSRIIFPAAYILFNLIYWSI 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	124/505 (25%)
GABRR1	NP_002033.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..55		5/22 (23%)
		LIC	75..478	CDD:273305	111/431 (26%)
		Neur_chan_LBD	76..281	CDD:280998	47/216 (22%)
		Neur_chan_memb	288..475	CDD:280999	58/202 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810