Protein Alignment CG12344 and GABRG3

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_011519732.1
• Gene: GABRG3 / 2567
• HGNCID: 4088
• Length: 473
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 123/436 - (28%)
• Similarity: 196/436 - (44%)
• Gaps: 64/436 - (14%)

  Fly    44 YVKEIRPPSKKG-SPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107
            |.|::||..  | .|.::|..|:|..|..::..:|::::|:|..|.|.:|||.     |......
Human    58 YDKKLRPDI--GIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKI 115

  Fly   108 VTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPM 172
            :||...:....|.||..|.|||.||...:|.....:.::.:..:.|..|:.....||::...:||
Human   116 LTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM 180

  Fly   173 DIQVCPIYIESFSSNNQKVKLRWSDSGVTL--NPELKLLQYNLGQPLELEESDGYMPEKVGNFSR 235
            |...||:...|:....:::..||..:.|..  ....:|.|::.   :.|..:...:....|::..
Human   181 DEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDF---MGLRNTTEIVTTSAGDYVV 242

  Fly   236 LTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DI 298
            :|:||...|::|:..|||:.|..|.|:|||.|||:..||.|.|..|.:|.:||:.|:.|.|  .:
Human   243 MTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSL 307

  Fly   299 PPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVAS 363
            |.|:||.|:||::..|.|.|||||.|:..:.      .|...|.|.......|.:....    :.
Human   308 PRVSYVTAMDLFVTVCFLFVFAALMEYATLN------YYSSCRKPTTTKKTTSLLHPDS----SR 362

  Fly   364 WEGGAVRSRKATQTPTTPGQTSLQG----NGGPPKPARRQSLLSVAWTD-TDTGVEKIM------ 417
            |    :..|.:.|.|:.  :.:||.    :..||..|......||.|.: .||.|.:.:
Human   363 W----IPERISLQAPSV--RIALQNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQ 421

  Fly   418 -------------WR---------EIDKVSRAVFPILFFVFVLLYW 441
                         ||         |:|..||..||..|.:|.|:||
Human   422 SFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYW 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	121/434 (28%)
GABRG3	XP_011519732.1	Neur_chan_LBD	48..253	CDD:280998	52/204 (25%)
		LIC	50..470	CDD:273305	123/436 (28%)
		Neur_chan_memb	260..467	CDD:280999	66/222 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820