Protein Alignment CG12344 and GABRG1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_775807.2
• Gene: GABRG1 / 2565
• HGNCID: 4086
• Length: 465
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 113/434 - (26%)
• Similarity: 194/434 - (44%)
• Gaps: 85/434 - (19%)

  Fly    44 YVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYV 108
            |..::||.... .|.:::..::|..|..::..:|::.:|:...|.|.:|||:     |......:
Human    75 YDNKLRPDIGV-RPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLK-----FNSTMKVL 133

  Fly   109 TLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMD 173
            .|...:....|.||.:|.||:.::...:|.....:.::.:..|.|..|:.....|.::...:|||
Human   134 MLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMD 198

  Fly   174 IQVCPIYIESFSSNNQKVKLRWSDSGVTL-NPEL-KLLQYNLGQPLELEESDGYMPEKVGNFSRL 236
            ...||:...|:.....:::.:|....|.: :|:. :|.|:..   :.|..|........|::..:
Human   199 EHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF---VGLRNSTEITHTISGDYVIM 260

  Fly   237 TVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIP 299
            |::|...|::|:..|||:.|..|.|:|||.|||:..||:|.|.:|.:|.:||:.|:.|.|  .:|
Human   261 TIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLP 325

  Fly   300 PVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASW 364
            .|:||.|:||:::.|.:.|||||.|:..:..                   .::.:||:.||
Human   326 KVSYVTAMDLFVSVCFIFVFAALMEYGTLHY-------------------FTSNQKGKTAT---- 367

  Fly   365 EGGAVRSR----KATQTP-TTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKI-------- 416
                 :.|    ||:.|| ..||.|.:..|.           :||...| |.|.:.:
Human   368 -----KDRKLKNKASMTPGLHPGSTLIPMNN-----------ISVPQED-DYGYQCLEGKDCASF 415

  Fly   417 ----------MWRE---------IDKVSRAVFPILFFVFVLLYW 441
                      .|||         ||..||..||..|.:|.|:||
Human   416 FCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYW 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	111/432 (26%)
GABRG1	NP_775807.2	LIC	66..462	CDD:273305	113/434 (26%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	38/188 (20%)
		Cys-loop	188..202	CDD:349801	4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820