Protein Alignment CG12344 and GABRA1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_000797.2
• Gene: GABRA1 / 2554
• HGNCID: 4075
• Length: 456
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 124/441 - (28%)
• Similarity: 202/441 - (45%)
• Gaps: 61/441 - (13%)

  Fly    31 NYTAKPRVV--LPPNYVKEIRPP-SKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLES 92
            |.|...|::  |...|...:||. .::.:.|..|  |||.....::..||::.:|:|..|.|.:.
Human    38 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTD--IFVTSFGPVSDHDMEYTIDVFFRQSWKDE 100

  Fly    93 RLEIPDDIFEEGDDYVTLLPEVF-ENFWQPDPYFLNSK--IAEIATLTHKFTSVTLYKNKTVRYA 154
            ||:.      :|...|..|..:. ...|.||.:|.|.|  :|...|:.:|...:|  ::.|:.|.
Human   101 RLKF------KGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT--EDGTLLYT 157

  Fly   155 ARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW----SDSGVTLNPELKLLQYN-LG 214
            .|:.....|.|..:.:|||...||:...|::....:|...|    :.|.|......:|.||: ||
Human   158 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLG 222

  Fly   215 QPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRV 279
            |.::    .|.:....|.:..:|.:|..:|:||:.:|||:.|..:.|:||..||||..:::|.|.
Human   223 QTVD----SGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 283

  Fly   280 TLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQ-YQYQVNR 341
            ...||.:||:.|:...|  .:|.|||..|:|.::|.|...||:||.||..|.....: |.:....
Human   284 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKS 348

  Fly   342 IPKVLPMRISN--MEKGQ--CATVASW--------EGGAVRSRKATQTPTTPGQTSLQGNGGPPK 394
            :....|.::.:  ::|..  ..|..|:        .|.|..::.||..|     ..::....||:
Human   349 VVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEP-----KEVKPETKPPE 408

  Fly   395 PARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILL 445
            |.:           |...|.|     ||::||..||:||.:|.|:||...|
Human   409 PKK-----------TFNSVSK-----IDRLSRIAFPLLFGIFNLVYWATYL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	121/435 (28%)
GABRA1	NP_000797.2	LIC	14..442	CDD:273305	123/438 (28%)
		LGIC_ECD_GABAAR_A1	56..249	CDD:349835	53/206 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820