Protein Alignment CG12344 and Glrb

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_445748.1
• Gene: Glrb / 25456
• RGDID: 2706
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 130/456 - (28%)
• Similarity: 220/456 - (48%)
• Gaps: 60/456 - (13%)

  Fly    40 LPPN------------YVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLES 92
            :|||            |...|| |:.||.||.|..:||:....||....||:||::|:.|:|.:.
  Rat    51 VPPNSTSNILNRLLVSYDPRIR-PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDP 114

  Fly    93 RLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARM 157
            ||::|.|.  .|.|.:|:.|.:::..|:||.:|.|.|.|....:|.:...:.::::..|..:.|:
  Rat   115 RLKLPSDF--RGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRL 177

  Fly   158 HAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNL-GQPLELEE 221
            ...::|.::..|:|||.|.|.:.:|||......::..|.........::.|.|::: .:.:|...
  Rat   178 SITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGN 242

  Fly   222 SDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCM 286
            ...|. :..|.::.:.|.|...||:|.:::..:||:.|:|:|||.|||:..||...||.|.:..:
  Rat   243 CTKYY-KGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSV 306

  Fly   287 LTLVTMFT--GADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVL---DVQYQYQVNRIPKV- 345
            |:|.:..|  .|::|.|:||||||:|:..|:|..||:|.|:.||:|:   ..:.:.:..||.|.
  Rat   307 LSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAE 371

  Fly   346 -------------------LPMRISNMEKGQ--CATVASWEGGAVRSRKATQTPTTPGQTSLQG- 388
                               .|:.||.::.|:  |..|.:.:.. :||...:...:.|....|..
  Rat   372 QADGKGGNAAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSD-LRSNDFSIVGSLPRDFELSNY 435

  Fly   389 ---------NGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPIL 444
                     |.|..||..:......|.....|..::     ||..:||:||..|..|.::||.|.
  Rat   436 DCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKR-----IDLYARALFPFCFLFFNVIYWSIY 495

  Fly   445 L 445
            |
  Rat   496 L 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	126/450 (28%)
Glrb	NP_445748.1	LIC	43..495	CDD:273305	128/453 (28%)
		LGIC_ECD_GlyR_beta	79..265	CDD:349811	50/188 (27%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	247..253		1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000