Protein Alignment alka and Gabra3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_058765.3
• Gene: Gabra3 / 24947
• RGDID: 2648
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 464
• Identity: 124/464 - (26%)
• Similarity: 212/464 - (45%)
• Gaps: 87/464 - (18%)

  Fly    31 NYTAKPRVV--LPPNYVKEIRPPSKKGSPVI-VDFSIFVVDINSINVEDMDFRVDMFIHQRWLES 92
            |.|...|::  |...|...:||  ..|..|. |...|:|.....::..||::.:|:|..|.|.:.
  Rat    63 NITIFTRILDRLLDGYDNRLRP--GLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDE 125

  Fly    93 RLEIPDDIFEEGDDYVTLLP---EVFENFWQPDPYFLNSKIAEIATLTHKFTS----VTLYKNKT 150
            ||:.        |..:.:||   .:....|.||.:|.|.|    .::.|..|:    :.|..|.|
  Rat   126 RLKF--------DGPMKILPLNNLLASKIWTPDTFFHNGK----KSVAHNMTTPNKLLRLVDNGT 178

  Fly   151 VRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPEL-----KLLQ 210
            :.|..|:.....|.|..:.:|||:..||:...|::....:|...|: .|...:.|:     :|.|
  Rat   179 LLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKAEVIYSWT-LGKNKSVEVAQDGSRLNQ 242

  Fly   211 YN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDA 274
            |: ||..:..|    .:....|.:..:|.:|..:|:||:.:|||:.|..:.|:||..||||..::
  Rat   243 YDLLGHVVGTE----IIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRES 303

  Fly   275 IPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQ-YQ 336
            :|.|....||.:||:.|:...|  .:|.|||..|:|.::|.|...||:||.||..|.....: :.
  Rat   304 VPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWA 368

  Fly   337 YQVNRIPKVLPMR-----------------------ISNMEKGQCATVASWEGGAVRSRKATQTP 378
            ::..::|:.|.|:                       |:..:..:.:|::.    |..:..|:.||
  Rat   369 WEGKKVPEALEMKKKTPAAPTKKTSTTFNIVGTTYPINLAKDTEFSTISK----AAAAPSASSTP 429

  Fly   379 T---TPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLY 440
            |   :|..|.:|.:     ||..::..||:              ::||:||.:||:||.:|.|:|
  Rat   430 TVIASPKTTYVQDS-----PAETKTYNSVS--------------KVDKISRIIFPVLFAIFNLVY 475

  Fly   441 WPILLMKSS 449
            |...:.:.|
  Rat   476 WATYVNRES 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	121/454 (27%)
Gabra3	NP_058765.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..54
		LIC	69..479	CDD:455710	121/451 (27%)
		LGIC_ECD_GABAAR_A3	75..274	CDD:349837	53/217 (24%)
		Cys-loop	191..205	CDD:349837	5/13 (38%)