DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12344 and Gabrp

DIOPT Version :9

Sequence 1:NP_001286298.1 Gene:CG12344 / 36145 FlyBaseID:FBgn0033558 Length:449 Species:Drosophila melanogaster
Sequence 2:NP_666129.1 Gene:Gabrp / 216643 MGIID:2387597 Length:440 Species:Mus musculus


Alignment Length:472 Identity:122/472 - (25%)
Similarity:225/472 - (47%) Gaps:79/472 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 ISFGLGFILMWLS--------EATEAHMNYTAKPRVVLP------PNYVKEIRPPSKKGSPVIVD 61
            :|:.|....:.||        :..:.::..:...::.||      ..|.|.:| |:..|.||.:.
Mouse     1 MSYSLYLAFLCLSLLTQRTCIQGNQVNVEVSRSDKLSLPGFENLTAGYNKFLR-PNFGGDPVRIA 64

  Fly    62 FSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFL 126
            .::.:..|:||:..:||:...:::.|||.:.||     :| ||:...||...:.|..|.||.|.:
Mouse    65 LTLDIASISSISESNMDYTATIYLRQRWTDPRL-----VF-EGNKSFTLDARLVEFLWVPDTYIV 123

  Fly   127 NSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKV 191
            .||.:.:..:|.....:.|:.|.||.||.|:...:.|.|:...||||.|.|.:.:||:..:...|
Mouse   124 ESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDV 188

  Fly   192 KLRW---SDSGVTLNPELKLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQT 253
            :..|   :||...|. .|:|.||.:.|...|..   ...::.||::||.:.|...|.:.:.:::|
Mouse   189 EFSWLRGNDSVRGLE-NLRLAQYTIQQYFTLVT---VSQQETGNYTRLVLQFELRRNVLYFILET 249

  Fly   254 FAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPV-AYVKALDLWMAGCM 315
            :.||:.:|:|||.|||:.||::|.|..:.||.:|::.|:..|:  .:|.. .::||:|:::..|.
Mouse   250 YVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICF 314

  Fly   316 LSVFAALAEFVVVKVLDVQYQYQVNRIP--KVLPMRISNMEKGQCATVASWEGGAVRSRKATQTP 378
            ..||.||.|:.|.....:|.....:|.|  ....:.|:|:..   ::::|::      ||.:   
Mouse   315 SFVFGALLEYAVAHYSSLQQMAVKDRGPAKDSEEVNITNIIN---SSISSFK------RKIS--- 367

  Fly   379 TTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTGVE---KIMWRE----------------IDKV 424
                ..|::.:|.           :|.::|......   |.::||                :|:.
Mouse   368 ----FASIEISGD-----------NVNYSDLTMKASDKFKFVFREKISRIIDYFTIQNPSNVDRY 417

  Fly   425 SRAVFPILFFVFVLLYW 441
            |:.:||::|.:..:.||
Mouse   418 SKLLFPLIFMLANVFYW 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12344NP_001286298.1 LIC 8..441 CDD:273305 120/470 (26%)
GabrpNP_666129.1 Neur_chan_LBD 41..242 CDD:280998 64/211 (30%)
LIC 43..437 CDD:273305 116/430 (27%)
Neur_chan_memb 249..434 CDD:280999 50/211 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3644
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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