Protein Alignment alka and Gabrr3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_620252.1
• Gene: Gabrr3 / 192258
• RGDID: 621564
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 134/500 - (26%)
• Similarity: 217/500 - (43%)
• Gaps: 107/500 - (21%)

  Fly    11 ISFGLGFI-LMWL------SEATEAHMNYTAKPRVVLPPNYVKEIRP---------PSKK----- 54
            ::|.|.|. ..|:      |...|.|....:.|:    ...::|.|.         |.|:
  Rat     3 LAFWLAFFTYTWITLMLDASAVKEPHQQCLSSPK----QTRIRETRMRKDDLTKVWPLKREQLLH 63

  Fly    55 -------------GSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDD 106
                         ||||.|...:.|..|:||:..:|||.:..::...|.:.||..|...    :.
  Rat    64 IEDHDFSTRPGFGGSPVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLSFPSTT----NK 124

  Fly   107 YVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYP 171
            .:|....:.:..|.||.:|::||.:.|...|.:...:.::.:..|.::.|:.....|.|:|..:|
  Rat   125 SMTFDRRLIQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFP 189

  Fly   172 MDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPE--LKLLQYNLGQPLELEESDGY-MPEKVGNF 233
            :|.|.|.:.:||::.|.:.:.|.|.....:||.|  :.|.|:.:.   |...|.|. .....|.:
  Rat   190 LDTQNCSLELESYAYNEEDLMLYWKHGNKSLNTEEHISLSQFFIE---EFSASSGLAFYSSTGWY 251

  Fly   234 SRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTG--A 296
            .||.:.|...|.|...::||:.|:.|:|||||.|||:...|:|.||:|.:|.:||:.|:.||  |
  Rat   252 YRLFINFVLRRHIFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIVTGVSA 316

  Fly   297 DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVL-DVQYQYQVNRIPKVLPMRISNMEKGQCAT 360
            .:|.|:||||:|::|....|.||.::.|:..|..| .|:...|:||..|     ||.|.......
  Rat   317 SMPQVSYVKAVDVYMWVSSLFVFLSVIEYAAVNYLTTVEEWKQLNRRGK-----ISGMYNIDAVQ 376

  Fly   361 VASWEG--------------------GAVRSRKATQTPTTPG----QTSLQGNGGPPKPARRQSL 401
            ..:::|                    .::|: |.|.:|....    :.||.||.|
  Rat   377 AMAFDGCYHDGETDVDQTSFFLHSEEDSMRT-KFTGSPCADSSQIKRKSLGGNVG---------- 430

  Fly   402 LSVAWTDTDTGVEKIMWRE---IDKVSRAVFPILFFVFVLLYWPI 443
                         :|:...   ||..||.|||:::.:|.|.||.|
  Rat   431 -------------RIILENNHVIDTYSRIVFPVVYIIFNLFYWGI 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	131/496 (26%)
Gabrr3	NP_620252.1	LIC	58..463	CDD:455710	121/440 (28%)
		LGIC_ECD	79..264	CDD:475126	50/191 (26%)
		Interaction with SQSTM1. /evidence=ECO:0000269|PubMed:12431995	344..445		24/129 (19%)