Protein Alignment CG12344 and lgc-52

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_502839.3
• Gene: lgc-52 / 190669
• WormBaseID: WBGene00013517
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 423
• Identity: 104/423 - (24%)
• Similarity: 182/423 - (43%)
• Gaps: 69/423 - (16%)

  Fly    39 VLPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEE 103
            :|..||.:...|   :.:||.|:..|.:.||:.|:.....|.:|.:|...|.:.||     .|..
 Worm    51 ILMTNYSRNALP---EPAPVKVEVEITIQDISDISAITGTFTIDYWISAIWNDKRL-----AFSH 107

  Fly   104 GD---DYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQM 165
            .|   ..::|..::....|.|:...:|||..::.........:.::.|.|:....|:.:...|||
 Worm   108 LDPCRKNLSLDHDMEPKLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTIWLNYRIRSEAPCQM 172

  Fly   166 EFQLYPMDIQVCPIYIESFSSNNQKVKLR---WSDSGVTLN----PELKLLQYNLGQPLELEESD 223
            ..:.:|:|...|.:..||:|.|...|:|:   ||......|    |:.::.....|...|...:
 Worm   173 NLRNFPLDSIRCSLVFESYSYNAADVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTEAYTA- 236

  Fly   224 GYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLT 288
                   |.:.||:|...|||..|.:::|.:.|:.:.|.:||.:||:...|:|.|:||.|:.::.
 Worm   237 -------GMWHRLSVSIHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMA 294

  Fly   289 LVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRIS 351
            |...|..  ..:|..:||||:|:||..|:..:|.:|.|..:|...|..:..::..:
 Worm   295 LTFQFGNIVKSLPKASYVKAIDIWMFSCVGFIFFSLIELAIVAYNDKMHDQRLREV--------- 350

  Fly   352 NMEKGQCATVASWEGGAVRSRKATQTPTTPGQTSLQGNG-GPPKPARRQSLLSVAWTDTDTGVEK 415
                 :|:.                       .:|..|| |......|:|.:.:: .....|.|
 Worm   351 -----RCSV-----------------------GNLNSNGIGQYNSTTRRSFVELS-ARRAKGSE- 385

  Fly   416 IMWREIDKVSRAVFPILFFVFVLLYWPILLMKS 448
             :...||:|:..:||.:|.:|.|:||...|..|
 Worm   386 -LGASIDRVASMLFPTMFALFNLVYWAYYLTTS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	100/414 (24%)
lgc-52	NP_502839.3	Neur_chan_LBD	45..248	CDD:280998	50/212 (24%)
		LIC	52..413	CDD:273305	102/416 (25%)
		Neur_chan_memb	259..>338	CDD:280999	27/78 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810