Protein Alignment CG12344 and lgc-55

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_507870.2
• Gene: lgc-55 / 180312
• WormBaseID: WBGene00013746
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 120/465 - (25%)
• Similarity: 197/465 - (42%)
• Gaps: 100/465 - (21%)

  Fly    51 PSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVT---LLP 112
            |..||  |.||..:.:..::.|:.......:.:...|.|.:..|...   .|||...:|   |..
 Worm   105 PKMKG--VDVDVELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFE---HEEGAHCLTNLSLSH 164

  Fly   113 EVFENFWQPDPYFLNSKIAEIATLTHKFTS----VTLYKNKTVRYAARMHAIIACQMEFQLYPMD 173
            .:.:|.|.|:...:|||.:.|    ||..:    :.::.|.||....|:.....|:|:|..:|||
 Worm   165 RMVDNIWLPNVCIVNSKGSAI----HKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFFPMD 225

  Fly   174 IQVCPIYIESFSSNNQKVKLRWSDSG--VTLNPELKLLQYNLGQPLELEESDGYMPEK------V 230
            ..:|....||::.|..||:|.|...|  |....::||..:::.:         ::.||      .
 Worm   226 RVMCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTK---------FVHEKATFIYPA 281

  Fly   231 GNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTG 295
            |.:.:|.:...|.|..|.:::|.:.|:..:|::||.||||...::|.||||.|:.::.|...::.
 Worm   282 GVWDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSN 346

  Fly   296 A--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNR---------IPKVLPMR 349
            .  .:|.|:|||.|||:|.||::.:|.::.|..||..|:.:.|.:.|.         |.|.:..|
 Worm   347 VSRSLPKVSYVKGLDLFMFGCIVYIFLSIVELAVVGSLEQRKQQRTNADGDFLSDDDIKKNIFQR 411

  Fly   350 ---ISNMEKG------QCATVASWEGGA----VRSRKATQT------PTTPGQTSLQGNGGP--- 392
               ..:.:.|      |.:..||.|.|.    .|:..|.:|      |..|     :.|..|
 Worm   412 TFSTKSFKSGYGARHHQFSECASPEDGGEWPKTRTEWAERTYVECPEPEPP-----ESNRHPEVE 471

  Fly   393 ---------------PKPARRQSLLS----VAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVL 438
                           ....||:.|:|    ..||..|          :|:..:.:|||.|....|
 Worm   472 NDSNNKMLVLVRQRRASRKRRKRLMSGKLFQRWTAED----------MDRFCQKLFPITFTFCNL 526

  Fly   439 LYWPILLMKS 448
            :||.....||
 Worm   527 IYWMYYTAKS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	116/456 (25%)
lgc-55	NP_507870.2	Neur_chan_LBD	88..295	CDD:280998	51/207 (25%)
		LIC	90..532	CDD:273305	118/459 (26%)
		Neur_chan_memb	304..>391	CDD:280999	32/86 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810