Protein Alignment alka and mod-1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_741580.1
• Gene: mod-1 / 179269
• WormBaseID: WBGene00003386
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 127/456 - (27%)
• Similarity: 200/456 - (43%)
• Gaps: 80/456 - (17%)

  Fly    43 NYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPD------DIF 101
            ||.|.:  |..:.| |.|:..|.|.|:.|:|....||.:|:...|.|.:|.|....      :|.
 Worm    44 NYTKML--PDAEDS-VQVNIEIHVQDMGSLNEISSDFEIDILFTQLWHDSALSFAHLPACKRNIT 105

  Fly   102 EEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQME 166
            .|    ..|||::    |.|:...:|||...:.....:...|.||:|.||....|:.....|.::
 Worm   106 ME----TRLLPKI----WSPNTCMINSKRTTVHASPSENVMVILYENGTVWINHRLSVKSPCNLD 162

  Fly   167 FQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNLGQPLELEESD--GYMPEK 229
            .:.:|.|.|.|.:..||:|.|:::|:|.|.:..|||.           :|::|.:.|  .|..:|
 Worm   163 LRQFPFDTQTCILIFESYSHNSEEVELHWMEEAVTLM-----------KPIQLPDFDMVHYSTKK 216

  Fly   230 V------GNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLT 288
            .      |.:.:|.|.|.|:|:.|.::||.:.|:.|.:::||.||.:...|:|.|.|:.::.:|.
 Worm   217 ETLLYPNGYWDQLQVTFTFKRRYGFYIIQAYVPTYLTIIVSWVSFCMEPKALPARTTVGISSLLA 281

  Fly   289 LVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRIS 351
            |...|..  .::|.|:||||:|:||.||:..||..:.|...|..:........|...:...||.|
 Worm   282 LTFQFGNILKNLPRVSYVKAMDVWMLGCISFVFGTMVELAFVCYISRCQNSVRNAERRRERMRNS 346

  Fly   352 NM-EKGQCATVASW--EGGAVRS-----------RKATQTPTTPGQTSLQGNGGPPKPARRQ--- 399
            .: ..|.|.|.::.  .||:|.|           .....||...|:.||..| |||.|...|
 Worm   347 QVWANGSCRTRSNGYANGGSVISHYHPTSNGNGNNNRHDTPQVTGRGSLHRN-GPPSPLNLQMTT 410

  Fly   400 --SLLSVAWTDTDTGVE----------------------KIMWREIDKVSRAVFPILFFVFVLLY 440
              |.:.:.:......:|                      :.....:||.|...||:.|.:|.|:|
 Worm   411 FDSEIPLTFDQLPVSMESDRPLIEEMRSTSPPPPSGCLARFHPEAVDKFSIVAFPLAFTMFNLVY 475

  Fly   441 W 441
            |
 Worm   476 W 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	125/454 (28%)
mod-1	NP_741580.1	LIC	7..479	CDD:455710	127/456 (28%)
		LGIC_ECD_GABAAR	56..238	CDD:349791	56/200 (28%)
		Cys-loop	159..173	CDD:349791	4/13 (31%)