Protein Alignment CG12344 and acc-1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001293865.1
• Gene: acc-1 / 177799
• WormBaseID: WBGene00010275
• Length: 470
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 116/467 - (24%)
• Similarity: 204/467 - (43%)
• Gaps: 74/467 - (15%)

  Fly    22 LSEATEAHMNYTAKPRVVLPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIH 86
            ::::.:...|.|.....:|..:|.|...|    ..|..|...::|.::.|::....||.:|::|:
 Worm    27 IAQSLDNCANDTEIINALLKDSYNKHYIP----SHPTHVRVDMWVQEVTSVSELTQDFEIDLYIN 87

  Fly    87 QRWLESRLEIPDDIFEEGDD---YVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKN 148
            :.|     |.|..::|:.:.   .::...:|.:..|.|:..|:|||.|.|.....|...:.::.|
 Worm    88 EFW-----EDPALVYEDMNPCKRNISFDDKVLQRLWLPNTCFINSKSAAIHESPFKNVFLMVFSN 147

  Fly   149 KTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSD-------SGVTLNPEL 206
            .|:....||.....|.|:.:.:|.|.|.|.:..|||:.|..:|:::|:.       ..:.| |:.
 Worm   148 GTLWTNYRMKLTGPCDMKLKRFPFDKQKCYLTFESFNYNTGEVRMQWNQPYPVILLKRIEL-PDF 211

  Fly   207 KLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLG 271
            ||:.:::   :.:|:.     ...|.:..|||.|.|||:.|.:::|.:.|:.:.:::||.||:||
 Worm   212 KLVNFSV---IAVEQM-----YPAGWWDELTVAFVFERRYGWYVLQGYIPTMVTIVISWISFYLG 268

  Fly   272 LDAIPGRVTLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQ 334
            ..|||.|..|.|..:|.:...|..  .::|.|:||||:|:||...||.:|.:|.|..||..:...
 Worm   269 PRAIPARTMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWMLSGMLFIFLSLLELAVVGFMSRN 333

  Fly   335 YQYQVNRIPKVLPMRISNMEKGQCATVA-SWEGGAVRSRKATQTP---------TTPGQTSLQGN 389
                     :.||.::...::.:..... ||        |:.||.         ......||:.:
 Worm   334 ---------EGLPPKVKKRKRQEDDDEGFSW--------KSMQTSPHLELRQFWVDKRVNSLRND 381

  Fly   390 GG-PPKPARRQSLLSVAWTDTDTGVEKIMW-----------RE-----IDKVSRAVFPILFFVFV 437
            .. ||........|...:.:.....||..|           ||     :|..|...||..:.:|.
 Worm   382 SAVPPVEDYAPMELEQPYQNITKRREKRKWMSGLRKKWRAMRELRPETVDFYSAIFFPTAYMLFN 446

  Fly   438 LLYWPILLMKSS 449
            :.||...|...|
 Worm   447 ISYWSFYLTSLS 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	112/457 (25%)
acc-1	NP_001293865.1	Neur_chan_LBD	38..243	CDD:280998	56/222 (25%)
		LIC	39..453	CDD:273305	112/448 (25%)
		Neur_chan_memb	251..450	CDD:280999	53/215 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810