Protein Alignment CG12344 and gab-1

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_499661.2
• Gene: gab-1 / 176691
• WormBaseID: WBGene00001512
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 125/510 - (24%)
• Similarity: 215/510 - (42%)
• Gaps: 141/510 - (27%)

  Fly    51 PSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRL----EIPDDIFEEGDDYVTLL 111
            |...|..:::...|.:...:||:..|||:.:.|::||.|.:.||    |||       .|.:||.
 Worm    71 PGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLRWSNEIP-------IDEMTLS 128

  Fly   112 PEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQV 176
            .|..:|.|.||.:..|.|.:.:..:|.:...:.:..:..|.|..|:.:.::|.|..:.:|:|.|.
 Worm   129 GEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSCSMNLRNFPLDSQN 193

  Fly   177 CPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNLGQPLE---LEESD-------GYMPE--- 228
            |.:.|||:.....:|.::|:                  .||.   :|::|       |:..|
 Worm   194 CTVEIESYGYTTSEVLMKWN------------------YPLAVHGVEQADVPQFTITGFHTEDSI 240

  Fly   229 ---KVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLV 290
               ..|::.||::.|:..|.:|:.:.||:.|..|:|||||.|||:..:|...||.|.:|.:||:.
 Worm   241 VSTATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMT 305

  Fly   291 TMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQY---------------- 337
            |:.||.  .:|.::|||::|:::..|.:.|||||.|:..     |.|.|
 Worm   306 TISTGVRQSLPRISYVKSIDIYLVMCFVFVFAALLEYAA-----VNYSYWGRERGKGGGGNEWPV 365

  Fly   338 ---------------------QVNRIPKVLPMRISNMEKGQCATVASWEGGAVRS----RKATQT 377
                                 .::.:|:....|:..:|:....:..:.:.....|    :|.:.:
 Worm   366 NGANKEDRESAVNVQKWVPSGLMDGVPQPQDRRVEALEEAMSTSNTAAQNNNFESTSKPKKRSSS 430

  Fly   378 PTTP----GQTSLQGNGGPPKP-------------------------------ARRQSL--LSVA 405
            |..|    |.|..:.:..|..|                               .||.:|  ::|:
 Worm   431 PIPPLCRAGNTISEESESPDYPRYSTTSLKGARPHASLNHKTHHLKGRSSARAKRRMTLARMNVS 495

  Fly   406 WTDTDTGVEK--------IMWRE---IDKVSRAVFPILFFVFVLLYWPILLMKSS 449
            ...:.:|:.:        |..|:   |||.||.|||:.|.||.|.||...:|..|
 Worm   496 MKQSISGIGRRARKVIPTIRVRDVNLIDKYSRVVFPVCFIVFNLFYWSYYMMVPS 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	121/500 (24%)
gab-1	NP_499661.2	LIC	67..545	CDD:273305	123/503 (24%)
		Neur_chan_LBD	68..259	CDD:280998	52/212 (25%)
		Neur_chan_memb	268..542	CDD:280999	66/278 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810