Protein Alignment alka and gab-1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_499661.2
• Gene: gab-1 / 176691
• WormBaseID: WBGene00001512
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 125/510 - (24%)
• Similarity: 215/510 - (42%)
• Gaps: 141/510 - (27%)

  Fly    51 PSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRL----EIPDDIFEEGDDYVTLL 111
            |...|..:::...|.:...:||:..|||:.:.|::||.|.:.||    |||       .|.:||.
 Worm    71 PGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLRWSNEIP-------IDEMTLS 128

  Fly   112 PEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQV 176
            .|..:|.|.||.:..|.|.:.:..:|.:...:.:..:..|.|..|:.:.::|.|..:.:|:|.|.
 Worm   129 GEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSCSMNLRNFPLDSQN 193

  Fly   177 CPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNLGQPLE---LEESD-------GYMPE--- 228
            |.:.|||:.....:|.::|:                  .||.   :|::|       |:..|
 Worm   194 CTVEIESYGYTTSEVLMKWN------------------YPLAVHGVEQADVPQFTITGFHTEDSI 240

  Fly   229 ---KVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLV 290
               ..|::.||::.|:..|.:|:.:.||:.|..|:|||||.|||:..:|...||.|.:|.:||:.
 Worm   241 VSTATGSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMT 305

  Fly   291 TMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQY---------------- 337
            |:.||.  .:|.::|||::|:::..|.:.|||||.|:..     |.|.|
 Worm   306 TISTGVRQSLPRISYVKSIDIYLVMCFVFVFAALLEYAA-----VNYSYWGRERGKGGGGNEWPV 365

  Fly   338 ---------------------QVNRIPKVLPMRISNMEKGQCATVASWEGGAVRS----RKATQT 377
                                 .::.:|:....|:..:|:....:..:.:.....|    :|.:.:
 Worm   366 NGANKEDRESAVNVQKWVPSGLMDGVPQPQDRRVEALEEAMSTSNTAAQNNNFESTSKPKKRSSS 430

  Fly   378 PTTP----GQTSLQGNGGPPKP-------------------------------ARRQSL--LSVA 405
            |..|    |.|..:.:..|..|                               .||.:|  ::|:
 Worm   431 PIPPLCRAGNTISEESESPDYPRYSTTSLKGARPHASLNHKTHHLKGRSSARAKRRMTLARMNVS 495

  Fly   406 WTDTDTGVEK--------IMWRE---IDKVSRAVFPILFFVFVLLYWPILLMKSS 449
            ...:.:|:.:        |..|:   |||.||.|||:.|.||.|.||...:|..|
 Worm   496 MKQSISGIGRRARKVIPTIRVRDVNLIDKYSRVVFPVCFIVFNLFYWSYYMMVPS 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	121/500 (24%)
gab-1	NP_499661.2	LIC	67..545	CDD:455710	123/503 (24%)