Protein Alignment CG12344 and Glrb

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_036018791.1
• Gene: Glrb / 14658
• MGIID: 95751
• Length: 530
• Species: Mus musculus
• Alignment Length: 479
• Identity: 129/479 - (26%)
• Similarity: 221/479 - (46%)
• Gaps: 82/479 - (17%)

  Fly    40 LPPN------------YVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLES 92
            :|||            |...|| |:.||.||.|..:||:....||....||:||::|:.|:|.:.
Mouse    61 VPPNSTSNILNRLLVSYDPRIR-PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDP 124

  Fly    93 RLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARM 157
            ||::|.|.  .|.|.:|:.|.:::..|:||.:|.|.|.|....:|.:...:.::::..|..:.|:
Mouse   125 RLKLPSDF--RGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRL 187

  Fly   158 HAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNL-GQPLELEE 221
            ...::|.::..|:|||.|.|.:.:|||......::..|.........::.|.|::: .:.:|...
Mouse   188 SITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGN 252

  Fly   222 SDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCM 286
            ...|. :..|.::.:.|.|...||:|.:::..:||:.|:|:|||.|||:..||...||.|.:..:
Mouse   253 CTKYY-KGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSV 316

  Fly   287 LTLVTMFT--GADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVL---DVQYQYQVNRIPKV- 345
            |:|.:..|  .|::|.|:||||||:|:..|:|..||:|.|:.||:|:   ..:.:.:..||.|.
Mouse   317 LSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAE 381

  Fly   346 -------------------LPMRISNMEK-------------GQCATVASWEGGAVRSRK--ATQ 376
                               .|:.||.:::             |......:.:.|..|.:|  .::
Mouse   382 QADGKGGNAAKKNTVNGTGTPVHISTLQELPMVCQQITYQLDGWPTDTLTTQVGETRCKKVCTSK 446

  Fly   377 TPTTPGQTSLQG--------------------NGGPPKPARRQSLLSVAWTDTDTGVEKIMWREI 421
            :.......|:.|                    |.|..||..:......|.....|..::     |
Mouse   447 SDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKR-----I 506

  Fly   422 DKVSRAVFPILFFVFVLLYWPILL 445
            |..:||:||..|..|.::||.|.|
Mouse   507 DLYARALFPFCFLFFNVIYWSIYL 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	125/473 (26%)
Glrb	XP_036018791.1	LIC	64..529	CDD:273305	125/473 (26%)
		LGIC_ECD_GlyR_beta	89..275	CDD:349811	50/188 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000