Protein Alignment alka and Gabrg2

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_032099.1
• Gene: Gabrg2 / 14406
• MGIID: 95623
• Length: 474
• Species: Mus musculus
• Alignment Length: 466
• Identity: 117/466 - (25%)
• Similarity: 209/466 - (44%)
• Gaps: 63/466 - (13%)

  Fly    17 FILMWLS--------EATEAHMNYTAKPRVVLPP----------------NYVKEIRPPSKKGSP 57
            :||:.||        ::.:.:.:|.:....||.|                .|..::||.... .|
Mouse    25 WILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGV-KP 88

  Fly    58 VIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPD 122
            .::...::|..|..:|..:|::.:|:|..|.|.:.||:     |......:.|...:....|.||
Mouse    89 TLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLK-----FNSTIKVLRLNSNMVGKIWIPD 148

  Fly   123 PYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSN 187
            .:|.|||.|:...:|.....:.::.:..|.|..|:.....||::...:|||...||:...|:...
Mouse   149 TFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYP 213

  Fly   188 NQKVKLRWSDSGVTLNP--ELKLLQYNLGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHL 250
            .:::..:|..|.|.:..  ..:|.|::.   :.|..:...:....|::..::|||...|::|:..
Mouse   214 REEIVYQWKRSSVEVGDTRSWRLYQFSF---VGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFT 275

  Fly   251 IQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAG 313
            |||:.|.:|:|:|||.|||:..||:|.|.:|.:|.:||:.|:.|.|  .:|.|:||.|:||:::.
Mouse   276 IQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSV 340

  Fly   314 CMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTP 378
            |.:.||:||.|:..:      :.:..||.|.   ......:|.....:.|::...:..|..:.|.
Mouse   341 CFIFVFSALVEYGTL------HYFVSNRKPS---KDKDKKKKNPLLRMFSFKAPTIDIRPRSATI 396

  Fly   379 TTPGQTSLQGN----GGPPKPARRQSLLSVAWTDTDTGVEKIMWR---------EIDKVSRAVFP 430
            .....|.||..    |......:..:.....:.|..||.    ||         ::|..:|..||
Mouse   397 QMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGA----WRHGRIHIRIAKMDSYARIFFP 457

  Fly   431 ILFFVFVLLYW 441
            ..|.:|.|:||
Mouse   458 TAFCLFNLVYW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	115/464 (25%)
Gabrg2	NP_032099.1	LIC	68..471	CDD:455710	109/423 (26%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	42/188 (22%)
		Cys-loop	189..203	CDD:349801	5/13 (38%)