Protein Alignment CG12344 and Gabra6

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_036012221.1
• Gene: Gabra6 / 14399
• MGIID: 95618
• Length: 459
• Species: Mus musculus
• Alignment Length: 414
• Identity: 110/414 - (26%)
• Similarity: 181/414 - (43%)
• Gaps: 81/414 - (19%)

  Fly    17 FILMWLSEA---TEAHMNYTAK--PRVV--LPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINV 74
            ||::||..|   .|...|:.::  .|::  |...|...:| |...|:...|...|:|.....::.
Mouse     9 FIILWLENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLR-PGFGGAVTEVKTDIYVTSFGPVSD 72

  Fly    75 EDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHK 139
            .:|::.:|:|..|.|.:.||:     |:...:.::|...:....|.||.:|.|.|    .::.|.
Mouse    73 VEMEYTMDVFFRQTWTDERLK-----FKGPAEILSLNNLMVSKIWTPDTFFRNGK----KSIAHN 128

  Fly   140 FTS----VTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGV 200
            .|:    ..|.:|.|:.|..|:.....|.|....:|||...||:...|::....::...|. .|.
Mouse   129 MTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKTEIIYTWK-KGP 192

  Fly   201 TLNPEL-----KLLQYNL-GQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSL 259
            ..:.|:     .||||:| ||.:..|.    :....|.:..:||||..:|::|:.:||.:.|..:
Mouse   193 LYSVEVPEESSSLLQYDLIGQTVSSET----IKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIM 253

  Fly   260 VVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAAL 322
            .|:||..|||:..:::|.|....:|.:||:.|:...|  .:|.|:|..|:|.::|.|...||:||
Mouse   254 TVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSAL 318

  Fly   323 AEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKA---TQTPTTP--- 381
            .||..|       .|..|                            ::|:||   .||..||
Mouse   319 IEFAAV-------NYFTN----------------------------LQSQKAERQAQTAATPPVA 348

  Fly   382 ---GQTSLQGN---GGPPKPARRQ 399
               ...|||..   ..||:..||:
Mouse   349 KSKASESLQAEIVVTAPPQKRRRR 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	110/414 (27%)
Gabra6	XP_036012221.1	LGIC_ECD_GABAAR_A6	42..239	CDD:349840	53/211 (25%)
		LGIC_TM_GABAAR_alpha	242..337	CDD:349854	35/129 (27%)
		TM1 helix	245..265	CDD:349854	9/19 (47%)
		TM2 helix	274..295	CDD:349854	5/20 (25%)
		TM3 helix	305..327	CDD:349854	9/28 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910