Protein Alignment CG12344 and Gabra2

DIOPT Version :9

• Sequence 1: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Alignment Length: 453
• Identity: 124/453 - (27%)
• Similarity: 203/453 - (44%)
• Gaps: 79/453 - (17%)

  Fly    27 EAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVIVDF-SIFVVDINSINVEDMDFRVDMFIHQR 88
            ||..|.|...|::  |...|...:||  ..|..:...| :|:|.....::..||::.:|:|..|:
Mouse    34 EAKNNITIFTRILDRLLDGYDNRLRP--GLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQK 96

  Fly    89 WLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSK--IAEIATLTHKFTSVTLYKNKTV 151
            |.:.||:     |:...:.:.|...:....|.||.:|.|.|  :|...|:.:|.  :.:..:.|:
Mouse    97 WKDERLK-----FKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL--LRIQDDGTL 154

  Fly   152 RYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW----SDSGVTLNPE-LKLLQY 211
            .|..|:.....|.|..:.:|||...||:...|::....:|...|    ||| |.:.|: .:|.||
Mouse   155 LYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDS-VQVAPDGSRLNQY 218

  Fly   212 N-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAI 275
            : |||.:..|.    :....|.::.:|.:|..:|:||:.:|||:.|..:.|:||..||||..:::
Mouse   219 DLLGQSIGKET----IKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

  Fly   276 PGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQ 338
            |.|....||.:||:.|:...|  .:|.|||..|:|.::|.|...||:||.||..|...
Mouse   280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF------- 337

  Fly   339 VNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRK------------------ATQTPT---TPG 382
                          .::|.     :|:|.:|.:.|                  |...|.   .|.
Mouse   338 --------------TKRGW-----AWDGKSVVNDKKKEKGSVMIQNNAYAVAVANYAPNLSKDPV 383

  Fly   383 QTSLQGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILL 445
            .:::..:...|:|.::..........|...|.|     ||::||.|||:||..|.|:||...|
Mouse   384 LSTISKSATTPEPNKKPENKPAEAKKTFNSVSK-----IDRMSRIVFPVLFGTFNLVYWATYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	121/447 (27%)
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	123/450 (27%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	55/215 (26%)
		Cys-loop	166..180	CDD:349836	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		2/18 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010