Protein Alignment alka and Rdl

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_316070.4
• Gene: Rdl / 1276697
• VectorBaseID: AGAMI1_011163
• Length: 555
• Species: Anopheles gambiae
• Alignment Length: 535
• Identity: 146/535 - (27%)
• Similarity: 232/535 - (43%)
• Gaps: 134/535 - (25%)

  Fly     1 MLDKFNTNAFI-SFGLGFILMWLSEATEAHMNYTAKPRVVLPPNYVKEIRPPSKKGSPVIVDFSI 64
            ||...|.:|.: ||.:|                           |.|.:| |:..|.||.|..::
Mosquito    48 MLGDVNISAILDSFSVG---------------------------YDKRVR-PNYGGPPVEVGVTM 84

  Fly    65 FVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSK 129
            :|:.|:|::...|||.:|.:..|.|.:.||....   ..|.:.:::..|..:|.|.||.:|:|.|
Mosquito    85 YVLSISSVSEVLMDFTLDFYFRQFWTDPRLAYRK---RPGVETLSVGSEFIKNIWVPDTFFVNEK 146

  Fly   130 IA--EIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVK 192
            .:  .|||.:::|  :.::.:.::..:.|:....:|.|..|.:|||.|:|.|.||||....:.::
Mosquito   147 QSYFHIATTSNEF--IRIHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIR 209

  Fly   193 LRWSD--SGVTLNPELKLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTF 254
            ..|.|  |.|.::.|::|.|:. ||......|    :....||:|||....:|.|.:|::|||.:
Mosquito   210 YFWKDGLSSVGMSSEVELPQFRVLGHRQRATE----INLTTGNYSRLACEIQFVRSMGYYLIQIY 270

  Fly   255 APSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMF--TGADIPPVAYVKALDLWMAGCMLS 317
            .||.|:|::||.||||..:|.|.||.|.||.:||:.|:.  |.|.:|.::|||::|:::..|.:.
Mosquito   271 IPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVM 335

  Fly   318 VFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCA---------TVASWEGGA----- 368
            |||:|.|:..|..:..:.|.:..|...:  .:|:..:|.|.|         .|||.....
Mosquito   336 VFASLLEYATVGYMAKRIQMRKQRFMAI--QKIAEQKKQQQADANHPPPPPPVASDHSHGHGHGH 398

  Fly   369 -----------VRSRKATQTPTTPGQTS------------------------------------- 385
                       :.||..|.....|...|
Mosquito   399 SHTHQHTPKQQMGSRSGTMQNVPPNMGSRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTINGGR 463

  Fly   386 ---LQGNGGPP--------------KPARRQSLLSVAWTDTDTGVEKIMW---REIDKVSRAVFP 430
               ..|.||||              :.|..|.|:     .....:.|::.   .:|||.||.|||
Mosquito   464 GGGQPGGGGPPPGGPPGGGGGGPDEESAAPQHLI-----HPGKDINKLLGITPSDIDKYSRIVFP 523

  Fly   431 ILFFVFVLLYWPILL 445
            :.|..|.|:||.|.|
Mosquito   524 VCFVCFNLMYWIIYL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	139/522 (27%)
Rdl	XP_316070.4	LIC	56..537	CDD:455710	141/524 (27%)
		LGIC_ECD_GABAR_RDL-like	78..261	CDD:349809	56/191 (29%)
		Cys-loop	180..194	CDD:349809	7/13 (54%)