Protein Alignment alka and gabrr1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_017949821.2
• Gene: gabrr1 / 100497913
• XenbaseID: XB-GENE-1013743
• Length: 478
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 129/514 - (25%)
• Similarity: 215/514 - (41%)
• Gaps: 105/514 - (20%)

  Fly     1 MLDKFNTNAFISFGLGFILMW-LSEATEAHMNYTAKPRVVLPPNYVKEIRP----------PSKK 54
            ||...|....|     |:|:| .:.:||:......|.   :|..|.:..||          ..|:
 Frog     1 MLTNSNVQTCI-----FLLLWGWTMSTESRTQQRVKG---VPELYKQGSRPHRQRREVHQESHKQ 57

  Fly    55 GSPVI-------------------------------------VDFSIFVVDINSINVEDMDFRVD 82
            ||||.                                     |...:.|..::||:..||||.:.
 Frog    58 GSPVFKRSPDITKSPLTKSEQLLRIDDHDFTMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 122

  Fly    83 MFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYK 147
            :::...|.:.||..|    ...:..:|....:.:..|.||.:|::||.:.|...|.....:.:..
 Frog   123 LYLRHYWKDERLSFP----SSNNQSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNIMLRVQP 183

  Fly   148 NKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPE--LKLLQ 210
            :..|.|:.|:.....|.|:|..:|:|.|.|.:.|||::.....:.|.|.:...:|..:  :.|.|
 Frog   184 DGKVLYSLRVTVTAMCNMDFSRFPLDTQSCSLEIESYAYTEDDLMLYWKNGNESLKTDDRISLSQ 248

  Fly   211 YNLGQ-----PLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 270
            :.:.:     .|....|.|:       ::||.:.|...|.|...|:||:.|::|:|||||.|||:
 Frog   249 FLIQEFHTTTRLAFYSSTGW-------YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWI 306

  Fly   271 GLDAIPGRVTLLVTCMLTLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDV 333
            ...|.|.||.|.:|.:||:.|:.||  |.:|.|:|:||:|:::....:.||.::.|:..|..|..
 Frog   307 DRRAAPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTT 371

  Fly   334 QYQYQVNR----------IPKVLPMRISNMEKGQCATVASW--EGGAVRSRKATQTPTTPGQTSL 386
            ..:.:..:          :|:...|..|:...|:...:.::  |.|....|...|......:.|
 Frog   372 VQERKERKMREKYPCTCGVPQPRSMMDSSYSDGEVNNLGNYVSENGDKEDRIMVQLALNAERNS- 435

  Fly   387 QGNGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILL 445
                     .||:|..:......||       ..|||.||.:||..:.:|.|:||.|.|
 Frog   436 ---------NRRKSQRAYVSMRIDT-------HAIDKYSRLIFPASYILFNLIYWCIFL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	122/501 (24%)
gabrr1	XP_017949821.2	LIC	76..474	CDD:455710	106/425 (25%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	46/195 (24%)
		Cys-loop	199..213	CDD:349806	6/13 (46%)