Protein Alignment alka and gabrg3

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_002931686.2
• Gene: gabrg3 / 100494037
• XenbaseID: XB-GENE-6041774
• Length: 446
• Species: Xenopus tropicalis
• Alignment Length: 434
• Identity: 116/434 - (26%)
• Similarity: 190/434 - (43%)
• Gaps: 87/434 - (20%)

  Fly    44 YVKEIRPPSKKG-SPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107
            |.|::||..  | .|.::|..|:|..|..::..:|::::|:|..|.|.:|||.     |......
 Frog    58 YDKKLRPDI--GIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKI 115

  Fly   108 VTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPM 172
            :||...:....|.||..|.|||.||...:|.....:.::.:..:.|..|:.....||::...:||
 Frog   116 LTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPM 180

  Fly   173 DIQVCPIYIESFSSNNQKVKLRWSDSGV-TLNPE-LKLLQYNLGQPLELEESDGYMPEKVGNFSR 235
            |...||:...|:....:::..||..:.| |.|.: .:|.|::.   :.|..:...:....|::..
 Frog   181 DEHSCPLIFSSYGYPREEMVYRWRKNSVETANQKSWRLYQFDF---MGLRNTTEIVKTSAGDYIV 242

  Fly   236 LTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DI 298
            :||||...|::|:..|||:.|..|.|:|||.|||:..||.|.|..|.:|.:||:.|:.|.|  .:
 Frog   243 MTVYFDLSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSL 307

  Fly   299 PPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVAS 363
            |.|:||.|:||::..|.|.|||||.|:..:..                   .|:.:|.:|
 Frog   308 PRVSYVTAMDLFVTVCFLFVFAALIEYAALNY-------------------YSSCKKPRC----- 348

  Fly   364 WEGGAVRSRKATQT--PTTPGQTSLQGNGGPPKPARRQSLLSVAWTDTDTG-------------- 412
                 .:.:|:..:  ...|..|.:..|.            |:.|.:.:..
 Frog   349 -----TKKKKSNYSVLDMRPPPTVITLNN------------SLYWQEFEEACVYECLDGKDCQSF 396

  Fly   413 ------VEKIMWR---------EIDKVSRAVFPILFFVFVLLYW 441
                  .:...||         |:|..||..||..|.:|.|:||
 Frog   397 FCCYDECKSGSWRRGRIHIDLLELDSYSRVFFPTSFLLFNLVYW 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	114/432 (26%)
gabrg3	XP_002931686.2	LIC	50..443	CDD:455710	116/434 (27%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	48/188 (26%)
		Cys-loop	171..185	CDD:349801	5/13 (38%)