Protein Alignment alka and gabra1

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 451
• Identity: 128/451 - (28%)
• Similarity: 203/451 - (45%)
• Gaps: 66/451 - (14%)

  Fly    23 SEATEAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVI-VDFSIFVVDINSINVEDMDFRVDMF 84
            |...|...|.|...|::  |...|...:||  ..|..|. |:..|||.....::..||::.:|:|
 Frog    29 STQDEIKDNTTIFTRILDRLLDGYDNRLRP--GLGERVTEVNTDIFVTSFGPVSDHDMEYTIDVF 91

  Fly    85 IHQRWLESRLEIPDDIFEEGDDYVTLLPEVF-ENFWQPDPYFLNSK--IAEIATLTHKFTSVTLY 146
            ..|.|.:.||:.      :|...|..|..:. ...|.||.:|.|.|  :|...|:.:|...:|
 Frog    92 FRQGWRDERLKF------KGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIT-- 148

  Fly   147 KNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPEL----- 206
            ::.|:.|..|:.....|.|..:.:|||...||:...|::....:|...|     |..|.|
 Frog   149 EDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYSW-----TREPSLSVVVA 208

  Fly   207 ----KLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWF 266
                :|.||: |||.:    :.|.:....|.:..:|.:|..:|:||:.:|||:.|..:.|:||..
 Frog   209 EDGSRLNQYDLLGQTV----ASGIVQSSTGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQV 269

  Fly   267 SFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLSVFAALAEFVVVK 329
            ||||..:::|.|....||.:||:.|:...|  .:|.|||..|:|.::|.|...||:||.||..|.
 Frog   270 SFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN 334

  Fly   330 VLDVQ-YQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRSRKATQTPTTPGQTSLQGNG--- 390
            ....: |.:....:....|.::.:....:..|.||    |..:...| .|..||..::..:.
 Frog   335 YFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAS----ATANYPPT-IPRDPGLATIAKSATIE 394

  Fly   391 -----GPPKPAR-RQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILL 445
                 ..||||. :::..||:              :||::||..||:||..|.|:||...|
 Frog   395 PKDIEPKPKPAEPKKTFNSVS--------------KIDRLSRIAFPLLFGTFNLVYWATYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	125/445 (28%)
gabra1	XP_031754594.1	LIC	11..440	CDD:455710	127/448 (28%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	55/211 (26%)
		Cys-loop	165..179	CDD:349835	5/13 (38%)