Protein Alignment alka and gabra6

DIOPT Version :10

• Sequence 1: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: XP_031754593.1
• Gene: gabra6 / 100488862
• XenbaseID: XB-GENE-6049732
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 478
• Identity: 126/478 - (26%)
• Similarity: 208/478 - (43%)
• Gaps: 81/478 - (16%)

  Fly    19 LMWL-----------SEATEAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVI-VDFSIFVVDI 69
            :||:           :..|.|:::.....|::  |...|...:||  ..|.||. |...|:|...
 Frog     5 IMWIYIFLCTGKALGNNITAANLHSENITRILDRLLDGYDNRLRP--SFGGPVTEVKTDIYVTSF 67

  Fly    70 NSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIA 134
            ..::..||::.:|:|..|.|::.||:     |:...:.:.|...:....|.||.:|.|.|    .
 Frog    68 GPVSDVDMEYTMDIFFRQTWVDERLK-----FDGPTEILRLNNLMVSKIWTPDTFFRNGK----K 123

  Fly   135 TLTHKFTS----VTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW 195
            ::.|..|:    ..:.:|.||.|..|:.....|.|....:|||...||:...|::....::...|
 Frog   124 SIAHNMTTPNKLFRIMQNGTVLYTMRLTIKAECPMRLMNFPMDGHACPLKFGSYAYPKSEIVYTW 188

  Fly   196 SDSGVTLNPEL-----KLLQYNL-GQPLELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTF 254
            . .|...:.|:     .||||:| ||.:..|.    :....|.:|...|.|..:|:||:::|.|:
 Frog   189 K-KGPLYSVEVPEESSSLLQYDLVGQKVSSET----LLSNTGEYSLQVVMFFLQRKIGYYIIHTY 248

  Fly   255 APSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKALDLWMAGCMLS 317
            .|.|:.|:||...||:..:::|.|....:|.:||:.|:...|  ..|.|:|..|:|.::|.|...
 Frog   249 IPCSMTVVLSQVVFWINKESVPARTVAGITTVLTMTTLSISARHSFPKVSYATAMDWFIAVCFAF 313

  Fly   318 VFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWEGGAVRS----------- 371
            ||:||.||..|       .|..|     |.::.:.|:..:.|.:|:....|...
 Frog   314 VFSALIEFAAV-------NYFTN-----LQIQKTMMKAAKKAALAAATARAENEFVTLSDSNCNL 366

  Fly   372 RKATQTPTTPGQTSLQG----------NGGPPKPARRQSLLSVAWTDTDTGVEKIMWREIDKVSR 426
            :|...:..:.|..|.:|          |.....|. |..:||...:...||..|     |||.:|
 Frog   367 KKRINSVASQGNQSTEGDLPLYEDSPYNEQTDIPT-RDHMLSDTTSSQHTGTSK-----IDKYAR 425

  Fly   427 AVFPILFFVFVLLYWPILLMKSS 449
            .:||:.|..|.|:||.:.|.|.:
 Frog   426 ILFPLSFAGFNLVYWVVYLSKDT 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alka	NP_610619.2	LIC	8..441	CDD:455710	122/468 (26%)
gabra6	XP_031754593.1	LIC	12..443	CDD:455710	122/464 (26%)
		LGIC_ECD	42..239	CDD:475126	55/212 (26%)