DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12344 and LOC100001259

DIOPT Version :9

Sequence 1:	NP_001286298.1	Gene:	CG12344 / 36145	FlyBaseID:	FBgn0033558	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_021336767.1	Gene:	LOC100001259 / 100001259	-ID:	-	Length:	369	Species:	Danio rerio

Alignment Length:	387	Identity:	110/387 - (28%)
Similarity:	178/387 - (45%)	Gaps:	39/387 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLDKFNTNAFISFGLGFILMWLSEATEAHM-------NYTAKPRVV--LPPNYVKEIRPPSKKGS 56
            |.::|..:..: |.|  .|.|.:.:..|..       |.|...|::  |...|...:||  ..|.
Zfish     1 MRERFAVHLLV-FAL--TLFWHTRSVSADATTDAFKNNITLFTRILDRLLDGYDNRLRP--GLGD 60

  Fly    57 PV-IVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDYVTLLPEVFENFWQ 120
            .| .|...|:|.....::..||::.:|:|..|.|.:.||:     ||...:.:.|...:....|.
Zfish    61 RVTTVKTDIYVTSFGPVSDTDMEYTIDVFFRQSWKDERLK-----FEGPMNILRLNNLMASKIWT 120

  Fly   121 PDPYFLNSK--IAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIES 183
            ||.:|.|.|  :|...|:.:|.  :.:..:.|:.|..|:.....|.|..:.:|||...||:...|
Zfish   121 PDTFFHNGKKSVAHNMTMPNKL--LRIQDDGTLLYTMRLTVHAECPMHLEDFPMDFHSCPLKFGS 183

  Fly   184 FSSNNQKVKLRW----SDSGVTLNPELKLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFE 243
            ::....:|...|    |:|.|......:|.||: |||.:..|.    :....|.::.:|.:|..:
Zfish   184 YAYTTTEVTYTWTKNASNSVVVEEESSRLNQYDLLGQTVGNET----IRSSTGEYTVMTAHFHLK 244

  Fly   244 RQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLVTMFTGA--DIPPVAYVKA 306
            |:||:.:|||:.|..:.|:||..||||..:::|.|....||.:||:.|:...|  .:|.|||..|
Zfish   245 RKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 309

  Fly   307 LDLWMAGCMLSVFAALAEFVVVKVLDVQ-YQYQVNRIPKVLPMRISNMEKGQCATVASWEGG 367
            :|.::|.|...||:||.||..|.....: :.:....:.....|.|:....|.||.   |.||
Zfish   310 MDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKVMIINQRPAGLCAV---WLGG 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	108/380 (28%)
LOC100001259	XP_021336767.1	Neur_chan_LBD	7..>350	CDD:332142	100/358 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920