DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12325 and CG6015

DIOPT Version :10

Sequence 1:NP_610618.1 Gene:CG12325 / 36144 FlyBaseID:FBgn0033557 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_651005.1 Gene:CG6015 / 42593 FlyBaseID:FBgn0038927 Length:576 Species:Drosophila melanogaster


Alignment Length:469 Identity:100/469 - (21%)
Similarity:178/469 - (37%) Gaps:96/469 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   223 SDLEDAERPKIAPPQRKKEKKAVSDNESEDDVENVVEKDALKEESTKEAEDVNHIKNEDETKSHP 287
            |..:|..:....||:.||.:|. ..|::.:|:|..:......|.....|:     .||.|.....
  Fly   156 SAYDDNGKTVFEPPKAKKLRKQ-EKNDNPEDIEGFLGPWGKFENEVSVAK-----PNEQERAELD 214

  Fly   288 FFYKKITRHYLA----DEPRKEQRDVQL-TAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSLS 347
            ....|  ||...    |:|.:|:..:.: .|.:|..|:            ||:...|:.:  :|.
  Fly   215 ELLSK--RHKRGRIPEDKPLEEKSTLHIKDAYDYQGRS------------YLHAPHDLGV--NLR 263

  Fly   348 ISDYPISAALFNCTGDWVALASREIGQLLVWEWQSEQYIMKQQGHSSEMTCIA-YSSDGQFIATG 411
            .:..|....|                        .:.:|....||:..::.|. :......:.:|
  Fly   264 SNAPPTKCFL------------------------PKAHIHTWSGHNKGISSIRWFPKTAHLLLSG 304

  Fly   412 GEDSKVKLWNTQSS-FCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFD------VNRYRN 469
            ..|.:||||..... .|..|||.|...:..|.::......:|:|.|..::.:|      |:|   
  Fly   305 SMDCRVKLWEVYGERRCIRTFSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSR--- 366

  Fly   470 FRTFTSPNPAQFSCVAVDYSGE-LVVAGGQDVFDIFLWSVKTGKLLEIISGHEGPVVSIAFSPVA 533
            |.|...|...:|.   .|.|.: |.|||..|. .|..|..::|.:::....|.|.|.:|.|  |.
  Fly   367 FTTRKMPFCVKFH---PDNSKQHLFVAGTSDK-KIICWDTRSGDIVQEYDRHLGSVSTITF--VD 425

  Fly   534 TSSTLVSGSWDKTVKIWNC-LESNSEHETIDAVSDVTNVTFSPSGEEIAVATLSGNITIFDIKSA 597
            .:...|:.|.||:::||.. :..:.::.....:..:..||.:|:|:.:|..:|...|.||...: 
  Fly   426 DNRRFVTTSDDKSMRIWEWDIPVDMKYIADPTMHSMPAVTLAPNGKWMACQSLDNKIVIFSALN- 489

  Fly   598 GQVTTIEGRNDLSAGRLETDIITARKNAQANYFSTIEY----SADGECILAAGKSA--------- 649
                    |..::..:..|..:.:....|.::...:.|    ..||:|.:...|:.         
  Fly   490 --------RFKMNRKKTFTGHMVSGYACQLDFSPDMSYLVSGDGDGKCYIWDWKTTKMYKKWQAH 546

  Fly   650 -NICI---YHVREA 659
             .:||   :|..||
  Fly   547 DGVCISALWHPHEA 560

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12325NP_610618.1 WD40 <20..424 CDD:441893 40/206 (19%)
WD40 repeat 59..94 CDD:293791
WD40 repeat 99..143 CDD:293791
WD40 repeat 149..187 CDD:293791
WD40 repeat 192..247 CDD:293791 7/23 (30%)
WD40 306..657 CDD:441893 77/378 (20%)
WD40 repeat 353..391 CDD:293791 2/37 (5%)
WD40 repeat 397..433 CDD:293791 10/37 (27%)
WD40 repeat 438..474 CDD:293791 9/41 (22%)
WD40 repeat 482..518 CDD:293791 10/36 (28%)
WD40 repeat 524..557 CDD:293791 10/33 (30%)
WD40 repeat 565..594 CDD:293791 9/28 (32%)
Utp12 793..895 CDD:461125
CG6015NP_651005.1 WD40 277..576 CDD:238121 70/302 (23%)
WD40 repeat 289..327 CDD:293791 10/37 (27%)
WD40 repeat 332..368 CDD:293791 7/38 (18%)
WD40 repeat 374..412 CDD:293791 11/41 (27%)
WD40 repeat 418..453 CDD:293791 10/36 (28%)
WD40 repeat 461..500 CDD:293791 10/47 (21%)
WD40 repeat 509..532 CDD:293791 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

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