DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12343 and Syf2

DIOPT Version :9

Sequence 1:	NP_610617.1	Gene:	CG12343 / 36143	FlyBaseID:	FBgn0033556	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_081056.1	Gene:	Syf2 / 68592	MGIID:	1915842	Length:	242	Species:	Mus musculus

Alignment Length:	220	Identity:	125/220 - (56%)
Similarity:	165/220 - (75%)	Gaps:	2/220 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AAEKLAERKARLLDLHKKRQEARTDNHQEVVAEDARKKLPKNWEARKRQAEWILADDKARAEAQA 71
            ||:|..:|..:..:||.||.|||..||||||.||.|.|||.||||:|.:.||.|.:::.:.|..|
Mouse    25 AAQKREQRLRKFRELHLKRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELQEEEKKKECAA 89

  Fly    72 AGKDYERLKLLEVSAVDADRIEKKKKRKDNPDLGFSTYEAQTARQYNRLVKSMPARDLEKYERQK 136
            .|:|||::||||:||.||:|.|::||:| |||||||.|.|...|||:||.|.:.. |:|.||||:
Mouse    90 RGEDYEKVKLLEISAEDAERWERRKKKK-NPDLGFSDYAAAQLRQYHRLTKQIKP-DMESYERQR 152

  Fly   137 EELGDAFYGGAHTTLHSRTKDTPGAINKMVTDLEQQIERRKKYSRRRIYNDDADVDFINERNSKF 201
            |:.|:.|:..:::.||.....:...|::||.|||:|||:|.||||||.||||||:|:|||||:||
Mouse   153 EKHGEDFFPTSNSLLHGTHVPSSEEIDRMVLDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKF 217

  Fly   202 NKKLDRFYSEHTAEIKQNLERGTAI 226
            |||.:|||.::|||||||||||||:
Mouse   218 NKKAERFYGKYTAEIKQNLERGTAV 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12343	NP_610617.1	SYF2	71..221	CDD:285444	87/149 (58%)
Syf2	NP_081056.1	SYF2	89..237	CDD:400506	87/149 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836069
Domainoid	1	1.000	177	1.000	Domainoid score	I3578
eggNOG	1	0.900	-	-		E1_KOG2609
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5993
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3216
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55400
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004947
OrthoInspector	1	1.000	-	-		oto92947
orthoMCL	1	0.900	-	-		OOG6_103856
Panther	1	1.100	-	-	LDO	PTHR13264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1436
SonicParanoid	1	1.000	-	-		X3486
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790